Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | PYGL | P06737 | 1/20 | 0.31 |
| ▸ | XBP1 | P17861 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.30 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4653922 | 1.00 | RAB9A (0.32) | RAB9AOPRM1ALDH1A1PYGLXBP1 | |
| SCHEMBL4143330 | 0.84 | OPRM1 (0.35) | RAB9AOPRM1ALDH1A1XBP1HTT | |
| SCHEMBL4143326 | 0.84 | OPRM1 (0.35) | RAB9AOPRM1ALDH1A1XBP1HTT | |
| SCHEMBL4910830 | 0.82 | OPRM1 (0.34) | RAB9AOPRM1ALDH1A1XBP1HTT | |
| SCHEMBL4910840 | 0.82 | OPRM1 (0.34) | RAB9AOPRM1ALDH1A1XBP1HTT | |
| SCHEMBL4654125 | 0.79 | PYGL (0.34) | RAB9AOPRM1ALDH1A1PYGLXBP1 | |
| SCHEMBL4654129 | 0.79 | PYGL (0.34) | RAB9AOPRM1ALDH1A1PYGLXBP1 | |
| SCHEMBL4652761 | 0.76 | KCNA5 (0.33) | RAB9AALDH1A1XBP1HTTMTNR1A | |
| SCHEMBL4652759 | 0.76 | KCNA5 (0.33) | RAB9AALDH1A1XBP1HTTMTNR1A | |
| SCHEMBL4914550 | 0.75 | RAB9A (0.32) | RAB9AALDH1A1XBP1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1658067-B1 | INDOLAMIDE DERIVATIVES WHICH POSSESS GLYCOGEN PHOSPHORYLASE INHIBITORY ACTIVITY | ASTRAZENECA AB (SE) | 2008-11-12 | — | — | EP | disclosed |