Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 3/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.34 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | XBP1 | P17861 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4143326 | 1.00 | OPRM1 (0.35) | OPRM1MTNR1AMTNR1BRAB9AMEN1 | |
| SCHEMBL4653922 | 0.84 | RAB9A (0.32) | OPRM1MTNR1AMTNR1BRAB9AMEN1 | |
| SCHEMBL4653920 | 0.84 | RAB9A (0.32) | OPRM1MTNR1AMTNR1BRAB9AMEN1 | |
| SCHEMBL4654125 | 0.83 | PYGL (0.34) | OPRM1RAB9AALDH1A1XBP1HTT | |
| SCHEMBL4654129 | 0.83 | PYGL (0.34) | OPRM1RAB9AALDH1A1XBP1HTT | |
| SCHEMBL4148783 | 0.81 | TOP2A (0.35) | RAB9ACYP3A4ALDH1A1XBP1HTT | |
| SCHEMBL4148786 | 0.81 | TOP2A (0.35) | RAB9ACYP3A4ALDH1A1XBP1HTT | |
| SCHEMBL4652759 | 0.81 | KCNA5 (0.33) | MTNR1AMTNR1BRAB9AMEN1CYP1A2 | |
| SCHEMBL4652761 | 0.81 | KCNA5 (0.33) | MTNR1AMTNR1BRAB9AMEN1CYP1A2 | |
| SCHEMBL4914550 | 0.80 | RAB9A (0.32) | RAB9AALDH1A1XBP1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090124682-A1 | Indan-Amide Derivatives with Glycogen Phosphorylase Inhibitory Activity | BIRCH ALAN MARTIN | 2009-05-14 | — | — | US | disclosed |
| US-20080064691-A1 | Heterocyclic Amide Derivatives Which Possess Glycogen Phosphorylase Inhibitory Activity | ASTRAZENECA AB (SE) | 2008-03-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080064691-A1 | Heterocyclic Amide Derivatives Which Possess Glycogen Phosphorylase Inhibitory Activity | PYGL, PYGM, GYS1 | OPRM1 816/4885MTNR1A 2014/4885MTNR1B 1913/4885 |
| US-20090124682-A1 | Indan-Amide Derivatives with Glycogen Phosphorylase Inhibitory Activity | PYGL, PYGM, GYS1 | OPRM1 4290/4885MTNR1A 4667/4885MTNR1B 4611/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.