SCHEMBL4654640

SCHEMBL4654640

O=[N+]([O-])c1ccc(-c2ccccc2I)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.50
LMNA P02545 1/20 0.50
HTR7 P34969 1/20 0.49
TDP1 Q9NUW8 2/20 0.49
MAPT P10636 1/20 0.49
SCN2A Q99250 1/20 0.47
POLB P06746 1/20 0.47
MAPK1 P28482 1/20 0.47
C1R P00736 1/20 0.46
APP P05067 1/20 0.46
MAOB P27338 1/20 0.45
PTPRC P08575 2/20 0.44
CES1 P23141 2/20 0.44
BCHE P06276 1/20 0.44
ACHE P22303 1/20 0.44
S100A4 P26447 1/20 0.44
L3MBTL1 Q9Y468 2/20 0.44
MEN1 O00255 1/20 0.44
CRHBP P24387 1/20 0.44
KMT2A Q03164 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoromethanesulfonic Acid SCHEMBL3987054 0.85 PTGS2 (0.40) ALDH1A1LMNAHTR7TDP1MAPT
SCHEMBL4654801 0.85 SMN1; SMN2 (0.46) ALDH1A1LMNAHTR7POLBMAPK1
SCHEMBL28240316 0.84 ALDH1A1 (0.58) ALDH1A1LMNAHTR7TDP1MAPT
SCHEMBL4653600 0.82 PTPN11 (0.47) ALDH1A1LMNAHTR7TDP1MAPT
SCHEMBL4654720 0.82 PTGS2 (0.38) ALDH1A1LMNAHTR7TDP1MAPT
SCHEMBL8137845 0.81 PTPRC (0.50) ALDH1A1LMNATDP1MAPTPOLB
SCHEMBL4654724 0.79 PTPN11 (0.50) LMNAHTR7MAPTMEN1KMT2A
SCHEMBL7821087 0.78 ALDH1A1 (0.74) ALDH1A1LMNAHTR7TDP1SCN2A
SCHEMBL27935278 0.78 POLB (0.58) ALDH1A1LMNATDP1MAPTPOLB
SCHEMBL5827236 0.78 ALDH1A1 (0.47) ALDH1A1LMNAHTR7TDP1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4565378-B1 METHODS FOR PRODUCING OPTICAL EFFECT LAYERS COMPRISING MAGNETIC OR MAGNETIZABLE PIGMENT PARTICLES AND EXHIBITING ONE OR MORE INDICIA SICPA HOLDING SA (CH) 2026-05-06 EP claimed
US-20260015799-A1 METHODS FOR PRODUCING OPTICAL EFFECT LAYERS COMPRISING MAGNETIC OR MAGNETIZABLE PIGMENT PARTICLES AND EXHIBITING ONE OR MORE INDICIA SICPA HOLDING SA (CH) 2026-01-15 US claimed
EP-4565378-A1 METHODS FOR PRODUCING OPTICAL EFFECT LAYERS COMPRISING MAGNETIC OR MAGNETIZABLE PIGMENT PARTICLES AND EXHIBITING ONE OR MORE INDICIA Sicpa Holding SA (CH) 2025-06-11 EP claimed
US-12311406-B2 Methods for producing optical effect layers comprising magnetic or magnetizable pigment particles and exhibiting one or more indicia SICPA HOLDING SA (CH) 2025-05-27 US claimed
US-20240238839-A1 METHODS FOR PRODUCING OPTICAL EFFECT LAYERS COMPRISING MAGNETIC OR MAGNETIZABLE PIGMENT PARTICLES AND EXHIBITING ONE OR MORE INDICIA SICPA HOLDING SA (CH) 2024-07-18 US claimed
WO-2024028408-A1 METHODS FOR PRODUCING OPTICAL EFFECT LAYERS COMPRISING MAGNETIC OR MAGNETIZABLE PIGMENT PARTICLES AND EXHIBITING ONE OR MORE INDICIA SICPA HOLDING SA (CH) 2024-02-08 WO claimed
EP-4313430-A1 METHODS FOR PRODUCING OPTICAL EFFECT LAYERS COMPRISING MAGNETIC OR MAGNETIZABLE PIGMENT PARTICLES AND EXHIBITING ONE OR MORE INDICIA Sicpa Holding SA (CH) 2024-02-07 EP claimed
WO-2022207692-A1 METHODS FOR PRODUCING OPTICAL EFFECT LAYERS COMPRISING MAGNETIC OR MAGNETIZABLE PIGMENT PARTICLES AND EXHIBITING ONE OR MORE INDICIA SICPA HOLDING SA (CH) 2022-10-06 WO claimed
EP-4565378-B1 METHODS FOR PRODUCING OPTICAL EFFECT LAYERS COMPRISING MAGNETIC OR MAGNETIZABLE PIGMENT PARTICLES AND EXHIBITING ONE OR MORE INDICIA SICPA HOLDING SA (CH) 2026-05-06 EP disclosed
EP-4352175-B1 HYBRID UV-LED RADIATION CURABLE PROTECTIVE VARNISHES FOR SECURITY DOCUMENTS SICPA HOLDING SA (CH) 2026-02-25 EP disclosed
US-20260015799-A1 METHODS FOR PRODUCING OPTICAL EFFECT LAYERS COMPRISING MAGNETIC OR MAGNETIZABLE PIGMENT PARTICLES AND EXHIBITING ONE OR MORE INDICIA SICPA HOLDING SA (CH) 2026-01-15 US disclosed
US-12391841-B2 Hybrid UV-LED radiation curable protective varnishes for security documents SICPA HOLDING SA (CH) 2025-08-19 US disclosed
US-12311406-B2 Methods for producing optical effect layers comprising magnetic or magnetizable pigment particles and exhibiting one or more indicia SICPA HOLDING SA (CH) 2025-05-27 US disclosed
EP-4509568-A1 RADIATION-CURABLE HYBRID PROTECTIVE VARNISHES FOR SECURITY DOCUMENTS Sicpa Holding SA (CH) 2025-02-19 EP disclosed
WO-2022258704-A1 HYBRID UV-LED RADIATION CURABLE PROTECTIVE VARNISHES FOR SECURITY DOCUMENTS SICPA HOLDING SA (CH) 2022-12-15 WO disclosed
WO-2022207658-A1 CATIONIC UV-LED RADIATION CURABLE PROTECTIVE VARNISHES FOR SECURITY DOCUMENTS SICPA HOLDING SA (CH) 2022-10-06 WO disclosed
WO-2022207692-A1 METHODS FOR PRODUCING OPTICAL EFFECT LAYERS COMPRISING MAGNETIC OR MAGNETIZABLE PIGMENT PARTICLES AND EXHIBITING ONE OR MORE INDICIA SICPA HOLDING SA (CH) 2022-10-06 WO disclosed
CN-103548167-A Organic compound and photovoltaic device comprising the same CRYSCADE SOLAR LTD 2014-01-29 CN disclosed
EP-1640804-B1 Positive-tone radiation-sensitive resin composition JSR CORP (JP) 2008-11-19 EP disclosed
EP-1640804-A2 Positive-tone radiation-sensitive resin composition JSR Corporation (JP) 2006-03-29 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260015799-A1 METHODS FOR PRODUCING OPTICAL EFFECT LAYERS COMPRISING MAGNETIC OR MAGNETIZABLE PIGMENT PARTICLES AND EXHIBITING ONE OR MORE INDICIA IK, TEX10, INCENP ALDH1A1 1748/4885LMNA 77/4885HTR7 3188/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.