Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 11/20 | 0.48 |
| ▸ | PPARA | Q07869 | 11/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11750858 | 0.91 | LTA4H (0.45) | PPARGPPARAFFAR1 | |
| SCHEMBL7170118 | 0.86 | PDE4B (0.55) | PPARGPPARAALDH1A1POLBFFAR1 | |
| SCHEMBL4367753 | 0.85 | MTNR1A (0.53) | ALDH1A1FFAR1GAA | |
| SCHEMBL7171301 | 0.84 | ALDH1A1 (0.45) | PPARGPPARAALDH1A1FFAR1 | |
| SCHEMBL7179626 | 0.84 | OGG1 (0.49) | PPARGPPARAALDH1A1FFAR1KMT2A | |
| Dimethylamine SCHEMBL11334834 | 0.82 | PPARG (0.45) | PPARGPPARAGAAKMT2A | |
| SCHEMBL9614339 | 0.82 | PPARA (0.68) | PPARGPPARA | |
| SCHEMBL9819006 | 0.80 | KMT2A (0.52) | PPARGPPARASIGMAR1FFAR1GAA | |
| SCHEMBL4654975 | 0.80 | TBXA2R (0.47) | PPARGPPARAALDH1A1FFAR1 | |
| SCHEMBL6384424 | 0.80 | HTR2A (0.47) | ALDH1A1GAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1289558-A2 | COMBINATIONS OF AN ENDOTHELIN RECEPTOR ANTAGONIST AND AN ANTIEPILEPTIC COMPOUND HAVING PAIN ALLEVIATING PROPERTIES OR ANALGESIC | WARNER-LAMBERT COMPANY LLC (US) | 2003-03-12 | — | — | EP | disclosed |
| EP-1192125-A2 | MONO- AND DISUBSTITUTED 3-PROPYL GAMMA-AMINOBUTYRIC ACIDS | WARNER-LAMBERT COMPANY (US) | 2002-04-03 | — | — | EP | disclosed |
| WO-2001091736-A2 | COMBINATIONS OF AN ENDOTHELIN RECEPTOR ANTAGONIST AND AN ANTIEPILEPTIC COMPOUND HAVING PAIN ALLEVIATING PROPERTIES OR ANALGESIC | WARNER-LAMBERT COMPANY (US) | 2001-12-06 | — | — | WO | disclosed |
| WO-2000076958-A2 | MONO- AND DISUBSTITUTED 3-PROPYL GAMMA-AMINOBUTYRIC ACIDS | WARNER-LAMBERT COMPANY (US) | 2000-12-21 | — | — | WO | disclosed |