Nifuroxime

Nifuroxime

SCHEMBL465511

O=[N+]([O-])c1ccc(/C=N/O)o1

nearest known ligand 0.76

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 5/20 0.76
MAPT P10636 5/20 0.76
KMT2A Q03164 5/20 0.76
TDP1 Q9NUW8 4/20 0.76
ALDH1A1 P00352 4/20 0.76
MEN1 O00255 4/20 0.76
KDM4E B2RXH2 3/20 0.76
SMN1; SMN2 Q16637 3/20 0.76
L3MBTL1 Q9Y468 3/20 0.76
RAB9A P51151 3/20 0.76
MITF O75030 2/20 0.76
NPSR1 Q6W5P4 2/20 0.76
NPC1 O15118 1/20 0.76
XBP1 P17861 1/20 0.76
CYP1A2 P05177 4/20 0.62
CYP3A4 P08684 3/20 0.62
HTT P42858 2/20 0.62
CYP2D6 P10635 2/20 0.62
HIF1A Q16665 2/20 0.62
TP53 P04637 1/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Nifuroxime SCHEMBL5025023 1.00 LMNA (0.76) LMNAMAPTKMT2ATDP1ALDH1A1
Nifuroxime SCHEMBL465512 1.00 LMNA (0.76) LMNAMAPTKMT2ATDP1ALDH1A1
SCHEMBL13461151 0.83 LMNA (0.73) LMNAMAPTKMT2ATDP1ALDH1A1
SCHEMBL10680727 0.83 LMNA (0.73) LMNAMAPTKMT2ATDP1ALDH1A1
SCHEMBL11779135 0.83 LMNA (0.73) LMNAMAPTKMT2ATDP1ALDH1A1
Furaguanidine SCHEMBL30455389 0.80 ALDH1A1 (0.73) LMNAMAPTKMT2ATDP1ALDH1A1
SCHEMBL13433883 0.79 LMNA (0.67) LMNAMAPTKMT2ATDP1ALDH1A1
SCHEMBL16232908 0.79 LMNA (0.67) LMNAMAPTKMT2ATDP1ALDH1A1
SCHEMBL183545 0.78 KMT2A (0.66) LMNAMAPTKMT2ATDP1ALDH1A1
Nitrofurazone SCHEMBL25416 0.77 LMNA (1.00) LMNAMAPTKMT2ATDP1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 841 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250268998-A1 METHODS OF TREATMENT FOR CANDIDA AURIS INFECTIONS LUNDQUIST INSTITUTE FOR BIOMEDICAL INNOVATION AT HARBOR-UCLA MEDICAL CENTER 2025-08-28 US claimed
EP-4101437-B1 BACTERIOSTATIC COMPOSITION, PREPARATION METHOD THEREFOR AND USE THEREOF SHENZHEN EULIKAN BIOTECHNOLOGY CO LTD (CN) 2025-06-11 EP claimed
US-12324830-B2 Methods of treatment for Candida auris infections LUNDQUIST INSTITUTE FOR BIOMEDICAL INNOVATION AT HARBOR-UCLA MEDICAL CENTER 2025-06-10 US claimed
WO-2025076059-A1 ROCAGLATE DERIVATIVES AND USES THEREOF TRUSTEES OF BOSTON UNIVERSITY (US) 2025-04-10 WO claimed
US-20220395481-A1 BACTERIOSTATIC COMPOSITION, PREPARATION METHOD THEREFOR, AND USE THEREOF SHENZHEN EULIKAN BIOTECHNOLOGY CO., LTD (CN) 2022-12-15 US claimed
EP-4101437-A1 BACTERIOSTATIC COMPOSITION, PREPARATION METHOD THEREFOR AND USE THEREOF Shenzhen Eulikan Biotechnology Co., Ltd. (CN) 2022-12-14 EP claimed
CN-113559264-A Methods of treating microbial infections including mastitis 罗达制药公司 2021-10-29 CN claimed
WO-2021160049-A1 BACTERIOSTATIC COMPOSITION, PREPARATION METHOD THEREFOR AND USE THEREOF 深圳优丽康生物技术有限公司 2021-08-19 WO claimed
CN-113144197-A Method of treating topical microbial infections 罗达制药公司 2021-07-23 CN claimed
CN-111285786-B Nifuroxazone hapten and artificial antigen as well as preparation method and application thereof 中国农业大学 2021-04-06 CN claimed
EP-0743573-A2 Method for obtaining image contrast migration imaging members XEROX CORPORATION (US) 1996-11-20 EP claimed
US-5563014-A SOFTENABLE LAYER CONTAINIG PHOTOSENSITIVE MARKING MATERIAL; TRANSPARENTIZING AGENT XEROX CORPORATION (US) 1996-10-08 US claimed
US-5514505-A SELECTIVE TRANSPARENTIZATION OF PHOTOSENSITIVE MIGRATION MARKING PARTICLES EMBEDDED NEAR THE SURFACE OF A SOFTENABLE LAYER SUPPORTED BY AN ELECTROCONDUCTIVE SUBSTRATE XEROX CORPORATION (US) 1996-05-07 US claimed
US-5482740-A Sustained release bactericidal cannula ROCHESTER MEDICAL CORPORATION (US) 1996-01-09 US claimed
EP-0617631-A4 SUSTAINED-RELEASE BACTERICIDAL CANNULA. ROCHESTER MEDICAL CORP (US) 1995-02-22 EP claimed
US-5357636-A Flexible protective medical gloves and methods for their use DRESDNER JR KARL P (US) 1994-10-25 US claimed
EP-0617631-A1 SUSTAINED-RELEASE BACTERICIDAL CANNULA ROCHESTER MEDICAL CORPORATION (US) 1994-10-05 EP claimed
US-5261896-A Sustained release bactericidal cannula ROCHESTER MEDICAL CORPORATION (US) 1993-11-16 US claimed
WO-1993011821-A1 SUSTAINED-RELEASE BACTERICIDAL CANNULA ROCHESTER MEDICAL CORPORATION (US) 1993-06-24 WO claimed
US-4102998-A INTRAUTERINE DEVICE WHICH RELEASES MEDICATION GUTNICK MORTON 1978-07-25 US claimed