Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.56 |
| ▸ | MAPT | P10636 | 6/20 | 0.52 |
| ▸ | MEN1 | O00255 | 5/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.52 |
| ▸ | GAA | P10253 | 4/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 2/20 | 0.49 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.49 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3322371 | 0.92 | ALDH1A1 (0.59) | ALDH1A1MAPTMEN1KMT2AGAA | |
| SCHEMBL13832433 | 0.87 | ALDH1A1 (0.51) | ALDH1A1MAPTMEN1KMT2AGAA | |
| SCHEMBL14110955 | 0.86 | ALDH1A1 (0.61) | ALDH1A1MAPTMEN1KMT2AGAA | |
| SCHEMBL9499751 | 0.83 | LMNA (0.56) | ALDH1A1MAPTMEN1KMT2AGAA | |
| SCHEMBL29588009 | 0.81 | ALDH1A1 (0.52) | ALDH1A1MAPTMEN1KMT2AGAA | |
| SCHEMBL4535542 | 0.81 | ALDH1A1 (0.52) | ALDH1A1MAPTMEN1KMT2AGAA | |
| SCHEMBL8645160 | 0.80 | ALDH1A1 (0.57) | ALDH1A1MAPTSMN1; SMN2POLBPKM | |
| SCHEMBL3380429 | 0.80 | EGFR (0.58) | ALDH1A1MAPTMAPK1SMN1; SMN2POLB | |
| SCHEMBL8643871 | 0.80 | LMNA (0.52) | ALDH1A1MAPTMEN1KMT2AGAA | |
| SCHEMBL109663 | 0.80 | HTT (0.58) | ALDH1A1MAPTGAAMAPK1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1852414-B1 | Process for the preparation of 4-Hydroxyalkylamino-2-nitro-anisoles | WELLA AG (DE) | 2008-11-26 | — | — | EP | disclosed |
| US-7405325-B2 | Process for the preparation of 4-hydroxalkylamino-2-nitro-anisoles | THE PROCTER & GAMBLE COMPANY (US) | 2008-07-29 | — | — | US | disclosed |
| EP-1852414-A1 | Process for the preparation of 4-Hydroxyalkylamino-2-nitro-anisoles | Wella Aktiengesellschaft (DE) | 2007-11-07 | — | — | EP | disclosed |
| WO-2007122579-A2 | PROCESS FOR THE PREPARATION OF 4-HYDROXYALKYLAMINO-2-NITRO-ANISOLES | THE PROCTER & GAMBLE COMPANY (US) | 2007-11-01 | — | — | WO | disclosed |
| US-20070249868-A1 | New process for the preparation of 4-hydroxalkylamino-2-nitro-anisoles | WELLA OPERATIONS US, LLC | 2007-10-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070249868-A1 | New process for the preparation of 4-hydroxalkylamino-2-nitro-anisoles | HAO2, HCN2, NISCH | ALDH1A1 1176/4885MAPT 4743/4885MEN1 3853/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.