SCHEMBL3322371

SCHEMBL3322371

COc1ccc(NCCO)cc1[N+](=O)[O-]

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 9/20 0.59
MAPT P10636 5/20 0.54
MEN1 O00255 5/20 0.54
KMT2A Q03164 5/20 0.54
GAA P10253 3/20 0.52
MAPK1 P28482 2/20 0.52
SMN1; SMN2 Q16637 2/20 0.52
KDM4E B2RXH2 1/20 0.52
L3MBTL1 Q9Y468 1/20 0.52
POLB P06746 2/20 0.52
LMNA P02545 1/20 0.51
PKM P14618 1/20 0.51
CYP3A4 P08684 1/20 0.49
TSHR P16473 1/20 0.49
TDP1 Q9NUW8 1/20 0.49
PRMT5 O14744 1/20 0.48
WDR77 Q9BQA1 1/20 0.48
NPC1 O15118 2/20 0.47
RAB9A P51151 2/20 0.47
TUBB4A P04350 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4655115 0.92 ALDH1A1 (0.56) ALDH1A1MAPTMEN1KMT2AGAA
SCHEMBL4535542 0.89 ALDH1A1 (0.52) ALDH1A1MAPTMEN1KMT2AGAA
SCHEMBL29588009 0.89 ALDH1A1 (0.52) ALDH1A1MAPTMEN1KMT2AGAA
SCHEMBL14110955 0.88 ALDH1A1 (0.61) ALDH1A1MAPTMEN1KMT2AGAA
SCHEMBL9499751 0.86 LMNA (0.56) ALDH1A1MAPTMEN1KMT2AGAA
SCHEMBL11275885 0.84 TDP1 (0.56) ALDH1A1MAPTKDM4ETSHRTDP1
SCHEMBL13832433 0.84 ALDH1A1 (0.51) ALDH1A1MAPTMEN1KMT2AGAA
SCHEMBL5158792 0.81 ALDH1A1 (0.45) ALDH1A1MAPTMEN1KMT2AGAA
SCHEMBL2938667 0.81 MEN1 (0.54) ALDH1A1MAPTMEN1KMT2AMAPK1
SCHEMBL4761972 0.81 ALDH1A1 (0.56) ALDH1A1MAPTMEN1KMT2AGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 157 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9993413-B2 Keratin fibre dyeing composition BEAUTY & BUSINESS S.P.A. (IT) 2018-06-12 US claimed
US-20170258695-A1 KERATIN FIBRE DYEING COMPOSITION BEAUTY & BUSINESS S.P.A. (IT) 2017-09-14 US claimed
WO-2008099332-A1 MULTISTEP HAIR COLOR REVITALIZING KIT AND ASSOCIATED METHODS THE PROCTER & GAMBLE COMPANY (US) 2008-08-21 WO claimed
US-20080189876-A1 Multistep hair color revitalizing kit and associated methods PROCTER & GAMBLE COMPANY, THE 2008-08-14 US claimed
US-12583876-B2 Branched organosilicon compound, method of preparing same, and related compositions DOW SILICONES CORPORATION (US) 2026-03-24 US disclosed
EP-3493878-B1 COSMETIC COMPOSITION COMPRISING CURED SILICONE MATERIALS DOW SILICONES CORP (US) 2025-10-08 EP disclosed
US-12398270-B2 Acrylate-functional branched organosilicon compound, method of preparing same, and copolymer formed therewith DOW SILICONES CORPORATION (US) 2025-08-26 US disclosed
US-12371535-B2 Branched organosilicon compound, method of preparing same, and copolymer formed therewith DOW SILICONES CORPORATION (US) 2025-07-29 US disclosed
US-12337052-B2 Hair treatment method that increases the bond density of damaged hair BEAUTY & BUSINESS S.P.A. (IT) 2025-06-24 US disclosed
US-12338259-B2 Branched organosilicon compound, method of preparing same, and copolymer formed therewith DOW SILICONES CORPORATION (US) 2025-06-24 US disclosed
EP-4548908-A1 PERMANENT OXIDATIVE HAIR-COLOURING COMPOSITIONS Beauty & Business SpA (IT) 2025-05-07 EP disclosed
US-20250134788-A1 PERMANENT OXIDATIVE HAIR-COLORING COMPOSITIONS BEAUTY & BUSINESS S.P.A. (IT) 2025-05-01 US disclosed
US-20070249868-A1 New process for the preparation of 4-hydroxalkylamino-2-nitro-anisoles WELLA OPERATIONS US, LLC 2007-10-25 US disclosed
EP-0641764-B1 Process for the preparation of hydroxyalkylaminonitrobenzene derivatives CLARIANT GMBH (DE) 1998-05-20 EP disclosed
EP-0633915-B1 A METHOD AND LIQUID COMPOSITION FOR THE PRODUCTION OF INDELIBLE SCRIPT ON A PAPER SUBSTRATE SEGALLA GABRIELE (IT) 1998-02-04 EP disclosed
US-5637354-A USING OXIDATIVE FIBER REACTIVE DYE SEGALLA GABRIELE (IT) 1997-06-10 US disclosed
US-5508467-A REACTING AN AMINE SUBSTITUTED BENZONITRILE WITH AN ACYLCHLORIDE IN APROTIC SOLVENT; REARRANGEMENT IN PRESENCE OF ABASE CASSELLA AKTIENGESELLSCHAFT (DE) 1996-04-16 US disclosed
EP-0641764-A2 Process for the preparation of hydroxyalkylaminonitrobenzene derivatives HOECHST AKTIENGESELLSCHAFT (DE) 1995-03-08 EP disclosed
EP-0633915-A1 A METHOD AND LIQUID COMPOSITION FOR THE PRODUCTION OF INDELIBLE SCRIPT ON A PAPER SUBSTRATE SEGALLA, Gabriele (IT) 1995-01-18 EP disclosed
WO-1993020160-A1 A METHOD AND LIQUID COMPOSITION FOR THE PRODUCTION OF INDELIBLE SCRIPT ON A PAPER SUBSTRATE SEGALLA GABRIELE (IT) 1993-10-14 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12583876-B2 Branched organosilicon compound, method of preparing same, and related compositions OXSR1, BRS3, NPSR1 ALDH1A1 3531/4885MAPT 4513/4885MEN1 383/4885
US-20070249868-A1 New process for the preparation of 4-hydroxalkylamino-2-nitro-anisoles HAO2, HCN2, NISCH ALDH1A1 1176/4885MAPT 4743/4885MEN1 3853/4885
US-12338259-B2 Branched organosilicon compound, method of preparing same, and copolymer formed therewith OXSR1, BRS3, ORC3 ALDH1A1 3760/4885MAPT 4390/4885MEN1 70/4885
US-12371535-B2 Branched organosilicon compound, method of preparing same, and copolymer formed therewith OXSR1, BRS3, OXER1 ALDH1A1 2965/4885MAPT 4188/4885MEN1 639/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.