SCHEMBL465621

SCHEMBL465621

CN1C(C)(C)CC([C](c2cc(C(C)(C)C)c(O)c(C(C)(C)C)c2)C2CC(C)(C)N(C)C(C)(C)C2)CC1(C)C

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.41
KDM4E B2RXH2 4/20 0.41
MAPT P10636 4/20 0.41
SMN1; SMN2 Q16637 3/20 0.39
NPSR1 Q6W5P4 1/20 0.39
CA2 P00918 3/20 0.39
CA1 P00915 2/20 0.39
HPGD P15428 2/20 0.39
HSD17B10 Q99714 2/20 0.39
ALOX15 P16050 2/20 0.39
ALOX12 P18054 1/20 0.39
APOBEC3G Q9HC16 1/20 0.39
GAA P10253 4/20 0.38
POLB P06746 2/20 0.38
LMNA P02545 2/20 0.38
TSHR P16473 2/20 0.38
THRB P10828 1/20 0.38
TYR P14679 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
MEN1 O00255 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7533828 0.84 CA2 (0.39) ALDH1A1KDM4EMAPTSMN1; SMN2NPSR1
SCHEMBL7477196 0.78 ALDH1A1 (0.36) ALDH1A1KDM4EMAPTSMN1; SMN2NPSR1
SCHEMBL465622 0.76 ALDH1A1 (0.40) ALDH1A1KDM4EMAPTSMN1; SMN2CA2
SCHEMBL30712631 0.75 ALDH1A1 (0.47) ALDH1A1KDM4EMAPTSMN1; SMN2NPSR1
SCHEMBL28878718 0.75 HTT (0.41) ALDH1A1MAPTSMN1; SMN2NPSR1CA2
SCHEMBL2949729 0.72 ALDH1A1 (0.39) ALDH1A1KDM4EMAPTNPSR1CA2
SCHEMBL11512617 0.71 HTT (0.49) ALDH1A1MAPTSMN1; SMN2NPSR1HPGD
SCHEMBL11512621 0.71 HTT (0.49) ALDH1A1MAPTSMN1; SMN2NPSR1HPGD
SCHEMBL15951766 0.71 ALDH1A1 (0.37) ALDH1A1KDM4EMAPTSMN1; SMN2CA2
SCHEMBL2949730 0.70 ALDH1A1 (0.37) ALDH1A1KDM4EMAPTSMN1; SMN2NPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1976948-B1 ANTIMICROBIAL PAINT BEYOND TECHNOLOGIES AUSTRALIA PTY LTD (AU) 2012-10-03 EP claimed
EP-1137703-A1 STABILIZED THERMOPLASTIC COMPOSITIONS GENERAL ELECTRIC COMPANY (US) 2001-10-04 EP claimed
WO-2000034373-A1 STABILIZED THERMOPLASTIC COMPOSITIONS GENERAL ELECTRIC COMPANY (US) 2000-06-15 WO claimed
EP-0430650-B1 Nylon molding compositions exhibiting improved protection against UV-light degradation HOECHST CELANESE CORP (US) 1996-02-14 EP claimed
US-5476604-A Crosslinked binder of polyvinyl alcohol HEWLETT-PACKARD COMPANY (US) 1995-12-19 US claimed
EP-3933002-B1 ACTINIC-RAY-CURABLE COATING COMPOSITION, CURED COATING FILM, COATED ARTICLE, AND METHOD FOR FORMING COATING FILM KANSAI PAINT CO LTD (JP) 2024-06-12 EP disclosed
US-20230167332-A1 STEERING WHEEL TOYODA GOSEI CO., LTD. (JP) 2023-06-01 US disclosed
CN-111094382-B Process for preparing polyisocyanates of (cyclo) aliphatic diisocyanates which are stable to flocculation in solvents 巴斯夫欧洲公司 2022-12-16 CN disclosed
CN-115427473-A Color stable curing agent compositions comprising water dispersible polyisocyanates 巴斯夫欧洲公司 2022-12-02 CN disclosed
CN-111465659-B Coating composition for sealing surfaces 瓦克化学股份公司 2022-09-27 CN disclosed
CN-111133024-B Color-stable curing compositions of polyisocyanates containing (cyclo) aliphatic diisocyanates 巴斯夫欧洲公司 2022-05-10 CN disclosed
US-20220119668-A1 ACTINIC-RAY-CURABLE COATING COMPOSITION, CURED COATING FILM, COATED ARTICLE, AND METHOD FOR FORMING COATING FILM KANSAI PAINT CO., LTD. (JP) 2022-04-21 US disclosed
WO-2001056998-A1 BLOOM-RESISTANT BENZOTRIAZOLE UV ABSORBERS AND COMPOSITIONS STABILIZED THEREWITH CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2001-08-09 WO disclosed
WO-2000034373-A1 STABILIZED THERMOPLASTIC COMPOSITIONS GENERAL ELECTRIC COMPANY (US) 2000-06-15 WO disclosed
US-6034166-A CROSSLINKED MULTILAYER FILM FORMING POLYMER; CONCURRENT CURING BEE CHEMICAL COMPANY (US) 2000-03-07 US disclosed
US-5962574-A SPRAYABLE, THERMOSETTING PROTECTIVE COATING; PLASTIC AUTOMOBILE PARTS BEE CHEMICAL COMPANY (US) 1999-10-05 US disclosed
EP-0893483-A2 Wet-on-wet primer with low film build U.V. light protection MORTON INTERNATIONAL, INC. (US) 1999-01-27 EP disclosed
US-5556730-A Charge injection barrier for positive charging organic photoconductor HEWLETT-PACKARD COMPANY (US) 1996-09-17 US disclosed
WO-1995010790-A1 HIGH REFRACTIVE INDEX PHOTOCHROMIC OPHTHALMIC ARTICLE PPG INDUSTRIES, INC. (US) 1995-04-20 WO disclosed
US-5096951-A Calcium hydroxystearate, 3-salicyloylamido-1,2,4-triazole or tris-2-tert butyl-4-thio-/2'-methyl-4'-hydroxy-5'-tert butyl/ phenyl-5-methyl phenyl phosphite metal deactivator; molded parts HOECHST CELANESE CORPORATION (US) 1992-03-17 US disclosed