Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 3/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | GAA | P10253 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | TYR | P14679 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL465621 | 0.84 | ALDH1A1 (0.41) | CA2CA1SMN1; SMN2NPSR1ALDH1A1 | |
| SCHEMBL7477196 | 0.82 | ALDH1A1 (0.36) | CA2CA1SMN1; SMN2NPSR1ALDH1A1 | |
| SCHEMBL9588684 | 0.80 | TSHR (0.47) | CA2CA1SMN1; SMN2NPSR1ALDH1A1 | |
| SCHEMBL9400310 | 0.69 | KMT2A (0.53) | CA2CA1SMN1; SMN2NPSR1ALDH1A1 | |
| SCHEMBL1264011 | 0.68 | TSHR (0.64) | SMN1; SMN2NPSR1ALDH1A1GAATDP1 | |
| SCHEMBL7511680 | 0.66 | GAA (0.48) | CA2CA1SMN1; SMN2NPSR1ALDH1A1 | |
| SCHEMBL9588919 | 0.65 | TSHR (0.43) | SMN1; SMN2ALDH1A1GAAHTTPKM | |
| SCHEMBL6173752 | 0.61 | APLNR (0.52) | ALDH1A1KDM4EMAPTTDP1ALOX15 | |
| SCHEMBL11619186 | 0.61 | LMNA (0.49) | CA2CA1SMN1; SMN2NPSR1ALDH1A1 | |
| SCHEMBL465622 | 0.61 | ALDH1A1 (0.40) | CA2CA1SMN1; SMN2ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0309402-B2 | N-substituted hindered amine stabilizers | CIBA SC HOLDING AG (CH) | 2002-06-12 | — | — | EP | disclosed |
| EP-0309402-B1 | N-substituted hindered amine stabilizers | CIBA GEIGY AG (CH) | 1995-01-11 | — | — | EP | disclosed |