SCHEMBL2024345

SCHEMBL2024345

CN1C(C)(C)CC(C(CC(=O)O)c2cc(C(C)(C)C)c(O)c(C(C)(C)C)c2)CC1(C)C

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CACNA1A O00555 1/20 0.39
CACNA2D1 P54289 1/20 0.39
CACNB1 Q02641 1/20 0.39
ALDH1A1 P00352 3/20 0.39
GLA P06280 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
KDM4E B2RXH2 2/20 0.36
MAPT P10636 2/20 0.36
LMNA P02545 1/20 0.36
GAA P10253 1/20 0.36
PKM P14618 1/20 0.36
ALOX15 P16050 1/20 0.36
TSHR P16473 1/20 0.36
ALOX12 P18054 1/20 0.36
HSD17B10 Q99714 1/20 0.36
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
MAOB P27338 6/20 0.34
GLRA3 O75311 1/20 0.34
GLRB P48167 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8394189 0.81 CACNA1A (0.32) CACNA1ACACNA2D1CACNB1ALDH1A1GLA
SCHEMBL679220 0.81 KMT2A (0.39) CACNA1ACACNA2D1CACNB1ALDH1A1GLA
SCHEMBL465622 0.79 ALDH1A1 (0.40) CACNA1ACACNA2D1CACNB1ALDH1A1SMN1; SMN2
SCHEMBL22260996 0.77 GAA (0.33) CACNA1ACACNA2D1CACNB1GAAPKM
SCHEMBL314423 0.77 HIF1A (0.43) CACNA1ACACNA2D1CACNB1ALDH1A1KDM4E
SCHEMBL28473322 0.77 GAA (0.33) CACNA1ACACNA2D1CACNB1GAAPKM
SCHEMBL2687906 0.76 CACNA1A (0.34) CACNA1ACACNA2D1CACNB1ALDH1A1SMN1; SMN2
SCHEMBL7030387 0.75 IDH1 (0.35) CACNA1ACACNA2D1CACNB1ALDH1A1KDM4E
SCHEMBL9626834 0.74 ALDH1A1 (0.39) CACNA1ACACNA2D1CACNB1ALDH1A1KDM4E
SCHEMBL11132053 0.74 CACNA1A (0.40) CACNA1ACACNA2D1CACNB1ALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 62 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3626772-A1 USE OF A MELAMINE BASED COMPOUND AND A HALS COMPOUND AS HEAT STABILIZER IN POLYMERS Borealis AG (AT) 2020-03-25 EP disclosed
EP-2758462-B1 STABILIZING OF ORGANIC MATERIAL WITH AMINO-TRIAZINE BASED MANNICH-COMPOUNDS BOREALIS AG (AT) 2018-03-07 EP disclosed
US-9546261-B2 Stabilizing of organic material with amino-triazine based mannich-compounds BOREALIS AG (AT) 2017-01-17 US disclosed
US-20160124123-A1 CELLULOSE ACYLATE FILM, POLARIZING PLATE, AND LIQUID CRYSTAL DISPLAY USING THE SAME FUJIFILM CORPORATION (JP) 2016-05-05 US disclosed
US-9315760-B2 Ashless lubricant composition VANDERBILT CHEMICALS, LLC (US) 2016-04-19 US disclosed
US-9034223-B2 Optical film and process for producing the same KONICA MINOLTA OPTO, INC. (JP) 2015-05-19 US disclosed
US-20150087568-A1 ASHLESS LUBRICANT COMPOSITION VANDERBILT CHEMICALS, LLC 2015-03-26 US disclosed
US-8922889-B2 Cellulose acylate film, protective film for polarizing plate, polarizing plate, and liquid crystal display device FUJIFILM CORPORATION (JP) 2014-12-30 US disclosed
US-20140235766-A1 Stabilizing of Organic Material with Amino-Triazine Based Mannich-Compounds BOREALIS AG (AT) 2014-08-21 US disclosed
US-8551372-B2 Process for producing an optical film KONICA MINOLTA OPTO, INC. (JP) 2013-10-08 US disclosed
US-5057562-A Using steric hindered amine stabilizer CIBA-GEIGY CORPORATION (US) 1991-10-15 US disclosed
US-5030243-A Applying to a polyamide/polyurethane web an aqueous liquid containing a 2,6-dimethyl-2,6-dialkylpiperidin-4-yl ether, ester or similar derivative CIBA-GEIGY CORPORATION (US) 1991-07-09 US disclosed
US-4839405-A HINDERED AMINE AND PHENOLIC ANTIOXIDANT, FORMAMIDINE COMPOUND PLASTICOLORS, INC. (US) 1989-06-13 US disclosed
US-4822833-A USING A MIXTURE OF A 2,2,6,6-TETRAALKYLPIPERIDINE AND AN ORGANOTIN CARBOXYLATE THERMAL STABILIZER; REDUCED TITANIUM OXIDE LEVELS; WEATHERPROOFING CIBA-GEIGY CORPORATION (US) 1989-04-18 US disclosed
US-4721531-A PIGMENT WITH GLYCOL PLASTICOLORS, INC. (US) 1988-01-26 US disclosed
US-4552885-A FOR LATEX PAINTS, TETRAALKYL PYRIDINES CIBA GEIGY CORPORATION (US) 1985-11-12 US disclosed
US-4426472-A TETRAALKYLPIPERIDINES CIBA-GEIGY CORPORATION (US) 1984-01-17 US disclosed
US-4315848-A PROTECTIVE COATING FOR AUTOMOBILES CIBA-GEIGY CORPORATION (US) 1982-02-16 US disclosed
US-4278589-A 2-[2-Hydroxy-3,5-di-(α,α-dimethylbenzyl)phenyl]-2H-benzotriazole and stabilized compositions CIBA-GEIGY CORPORATION (US) 1981-07-14 US disclosed
US-4278590-A AUTOMOBILE FINISHES CIBA-GEIGY CORPORATION (US) 1981-07-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140235766-A1 Stabilizing of Organic Material with Amino-Triazine Based Mannich-Compounds PCNA, SOD1, UBE2M CACNA1A 4856/4885CACNA2D1 4672/4885CACNB1 4818/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.