Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 3/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4656377 | 0.83 | TYR (0.52) | TYRALOX5HTTMEN1KMT2A | |
| SCHEMBL28045776 | 0.81 | TYR (0.50) | TYRALOX5HTTMEN1KMT2A | |
| SCHEMBL8848639 | 0.76 | ALOX5 (0.54) | TYRALOX5HTTMEN1KMT2A | |
| SCHEMBL27462834 | 0.76 | TYR (0.33) | TYR | |
| SCHEMBL184986 | 0.76 | CDK1 (0.39) | TYRHTTMAPK1NPC1HPGD | |
| SCHEMBL156399 | 0.75 | TYR (0.65) | TYRALOX5HTTMEN1KMT2A | |
| SCHEMBL10671033 | 0.75 | ALOX5 (0.49) | TYRALOX5HTTMEN1KMT2A | |
| SCHEMBL3382419 | 0.73 | TYR (0.63) | TYRALOX5HTTMEN1KMT2A | |
| SCHEMBL10790730 | 0.71 | TYR (0.61) | TYRALOX5HTTMEN1KMT2A | |
| SCHEMBL28932575 | 0.71 | HMGCR (0.46) | TYRALOX5HTTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996013264-A1 | ORAL HYPOGLYCEMIC AGENTS | ELI LILLY AND COMPANY (US) | 1996-05-09 | — | — | WO | disclosed |