Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 3/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.39 |
| ▸ | CNR1 | P21554 | 3/20 | 0.39 |
| ▸ | CNR2 | P34972 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.39 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | PPARD | Q03181 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | TNKS | O95271 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2730924 | 0.86 | GABRA1 (0.57) | GABRA1GABRB2CNR1CNR2MEN1 | |
| SCHEMBL27388475 | 0.82 | ENPP2 (0.36) | GABRA1GABRB2CNR1CNR2MEN1 | |
| SCHEMBL1233050 | 0.81 | — | — | |
| SCHEMBL28499025 | 0.81 | BACE1 (0.41) | GABRA1GABRB2CNR1CNR2MEN1 | |
| SCHEMBL30567518 | 0.80 | CNR1 (0.56) | GABRA1GABRB2CNR1CNR2MEN1 | |
| SCHEMBL9616136 | 0.78 | — | — | |
| SCHEMBL28309366 | 0.78 | CNR1 (0.47) | CNR1CNR2GAAHPGDNPSR1 | |
| SCHEMBL11880583 | 0.77 | GAA (0.46) | MEN1GAAMAPTKMT2AALDH1A1 | |
| SCHEMBL8101394 | 0.77 | CNR1 (0.46) | CNR1CNR2 | |
| SCHEMBL7108215 | 0.77 | HTR2C (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1033590-B1 | Ocular lens material | MENICON CO LTD (JP) | 2008-05-07 | — | — | EP | disclosed |
| US-6329445-B1 | Ocular lens material | MENICON CO., LTD (JP) | 2001-12-11 | — | — | US | disclosed |
| EP-1033590-A2 | Ocular lens material | Menicon Co., Ltd. (JP) | 2000-09-06 | — | — | EP | disclosed |