SCHEMBL4657204

SCHEMBL4657204

CCOC(=O)c1c(OC(=O)O)ccc(C(=O)OC)c1-c1ccccc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 7/20 0.51
SMN1; SMN2 Q16637 6/20 0.51
ALDH1A1 P00352 4/20 0.51
LMNA P02545 4/20 0.51
HPGD P15428 3/20 0.51
KDM4E B2RXH2 3/20 0.51
GAA P10253 2/20 0.51
NPC1 O15118 1/20 0.51
RAB9A P51151 1/20 0.51
NPSR1 Q6W5P4 1/20 0.51
TDP1 Q9NUW8 1/20 0.47
GRM6 O15303 1/20 0.46
MEN1 O00255 2/20 0.45
KMT2A Q03164 2/20 0.45
TP53 P04637 4/20 0.45
TSHR P16473 1/20 0.44
CYP1A2 P05177 2/20 0.43
CYP2C9 P11712 2/20 0.43
CYP3A4 P08684 1/20 0.43
CYP2D6 P10635 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4657202 0.80 SLC6A3 (0.50) MAPTALDH1A1LMNAKDM4EGAA
SCHEMBL1638835 0.78 TSHR (0.56) MAPTSMN1; SMN2ALDH1A1LMNAHPGD
SCHEMBL27570075 0.78 ALDH1A1 (0.50) MAPTSMN1; SMN2ALDH1A1LMNAHPGD
SCHEMBL27556717 0.76 ALDH1A1 (0.49) MAPTSMN1; SMN2ALDH1A1LMNAHPGD
SCHEMBL8365211 0.76 TSHR (0.66) MAPTSMN1; SMN2ALDH1A1LMNAHPGD
SCHEMBL27516692 0.76 LMNA (0.44) MAPTSMN1; SMN2ALDH1A1LMNAHPGD
SCHEMBL1638898 0.76 SLC6A3 (0.54) MAPTSMN1; SMN2ALDH1A1LMNAHPGD
SCHEMBL27528890 0.74 ADORA3 (0.51) MAPTSMN1; SMN2ALDH1A1LMNAHPGD
SCHEMBL9077219 0.73 SLC6A3 (0.41) MAPTSMN1; SMN2ALDH1A1LMNAHPGD
Biphenyl SCHEMBL5706044 0.73 TSHR (0.61) MAPTSMN1; SMN2ALDH1A1LMNAHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1996650-A2 FLAME RETARDANT POLYCARBONATE COMPOSITIONS HAVING GOOD TRANSPARENCY AND LOW HAZE, METHOD OF MANUFACTURE, AND ARTICLES PREPARED THEREFROM Sabic Innovative Plastics IP B.V. (NL) 2008-12-03 EP disclosed
WO-2008013579-A2 FLAME RETARDANT POLYCARBONATE COMPOSITIONS HAVING GOOD TRANSPARENCY AND LOW HAZE, METHOD OF MANUFACTURE, AND ARTICLES PREPARED THEREFROM SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2008-01-31 WO disclosed