Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | PLK1 | P53350 | 1/20 | 0.37 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | PDE4A | P27815 | 5/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 5/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 5/20 | 0.37 |
| ▸ | PDE4C | Q08493 | 5/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 5/20 | 0.37 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11772606 | 0.74 | KDM4E (0.40) | MAPTHTTNPC1GAAPLK1 | |
| SCHEMBL8761973 | 0.72 | ALDH1A1 (0.40) | MAPTTDP1GAAAPOBEC3GALDH1A1 | |
| SCHEMBL20369245 | 0.71 | ALDH1A1 (0.42) | MAPTHTTTDP1GAAPLK1 | |
| SCHEMBL10616922 | 0.68 | MAPT (0.43) | MAPTHTTL3MBTL1TDP1NPC1 | |
| SCHEMBL4656127 | 0.67 | MAPT (0.42) | MAPTHTTL3MBTL1TDP1GAA | |
| SCHEMBL17471539 | 0.66 | NPC1 (0.34) | MAPTHTTL3MBTL1TDP1NPC1 | |
| SCHEMBL11739037 | 0.65 | ALDH1A1 (0.40) | MAPTHTTTDP1PLK1ALDH1A1 | |
| SCHEMBL19130596 | 0.65 | ALDH1A1 (0.71) | MAPTHTTTDP1NPC1GAA | |
| SCHEMBL13728725 | 0.64 | ADORA2A (0.75) | MAPTHTTPDE4AADORA2APDE4B | |
| SCHEMBL6471986 | 0.64 | SLC9A1 (0.42) | MAPTALDH1A1KDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1996649-A1 | STABILIZER COMPOSITIONS FOR HALOGENATED POLYMERS WITH IMPROVED INITIAL COLOR AND IMPROVED COLOR MAINTENANCE | Baerlocher GmbH (DE) | 2008-12-03 | — | — | EP | disclosed |
| WO-2007104379-A1 | STABILIZER COMPOSITIONS FOR HALOGENATED POLYMERS WITH IMPROVED INITIAL COLOR AND IMPROVED COLOR MAINTENANCE | BAERLOCHER GMBH (DE) | 2007-09-20 | — | — | WO | disclosed |