Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
| ▸ | MGLL | Q99685 | 1/20 | 0.40 |
| ▸ | CTSL | P07711 | 5/20 | 0.39 |
| ▸ | CTSS | P25774 | 5/20 | 0.39 |
| ▸ | CTSB | P07858 | 3/20 | 0.39 |
| ▸ | CTSK | P43235 | 2/20 | 0.39 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | KLK1 | P06870 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | CA5A | P35218 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4657462 | 1.00 | OPRK1 (0.42) | OPRK1MGLLCTSLCTSSCTSB | |
| SCHEMBL5227254 | 0.93 | ATM (0.44) | CTSLCTSSCTSBCTSKCTRB1 | |
| SCHEMBL5227258 | 0.93 | ATM (0.44) | CTSLCTSSCTSBCTSKCTRB1 | |
| SCHEMBL3343122 | 0.92 | TRPM8 (0.44) | OPRK1MGLLCTSLCTSSCTSB | |
| SCHEMBL3343120 | 0.92 | TRPM8 (0.44) | OPRK1MGLLCTSLCTSSCTSB | |
| SCHEMBL5225794 | 0.91 | CTSL (0.39) | OPRK1MGLLCTSLCTSSCTSB | |
| SCHEMBL3343179 | 0.84 | TRPM8 (0.48) | CTSLCTSSCTSBCTSKATM | |
| SCHEMBL3343181 | 0.84 | TRPM8 (0.48) | CTSLCTSSCTSBCTSKATM | |
| SCHEMBL3342679 | 0.83 | TRPM8 (0.44) | CTSLCTSSCTSBCTSKCA2 | |
| SCHEMBL3550564 | 0.83 | TRPM8 (0.44) | CTSLCTSSCTSBCTSKCA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1996202-A1 | CHEMICAL COMPOUNDS | AstraZeneca AB (SE) | 2008-12-03 | — | — | EP | disclosed |
| WO-2007104933-A1 | CHEMICAL COMPOUNDS | ASTRAZENECA AB (SE) | 2007-09-20 | — | — | WO | disclosed |