SCHEMBL465752

SCHEMBL465752

O=C(O)c1ccccc1C(F)F

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.56
ALOX15 P16050 1/20 0.56
KMT2A Q03164 2/20 0.53
TDP1 Q9NUW8 2/20 0.53
GAA P10253 1/20 0.53
MAPT P10636 3/20 0.52
HDAC8 Q9BY41 1/20 0.52
KDM4E B2RXH2 2/20 0.48
HPGD P15428 2/20 0.48
CA12 O43570 1/20 0.48
CA1 P00915 1/20 0.48
CA2 P00918 1/20 0.48
HMGB1 P09429 1/20 0.48
CA4 P22748 1/20 0.48
CA6 P23280 1/20 0.48
CA7 P43166 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.48
CA9 Q16790 1/20 0.48
NAPRT Q6XQN6 1/20 0.48
CA14 Q9ULX7 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30281127 1.00 ALDH1A1 (0.56) ALDH1A1ALOX15KMT2ATDP1GAA
SCHEMBL6756199 0.86 ALDH1A1 (0.56) ALDH1A1ALOX15KMT2ATDP1GAA
SCHEMBL16322570 0.83 ALDH1A1 (0.52) ALDH1A1ALOX15KMT2ATDP1GAA
SCHEMBL31336042 0.83 ALB (0.59) ALDH1A1ALOX15KMT2ATDP1GAA
SCHEMBL4564296 0.83 ALDH1A1 (0.52) ALDH1A1ALOX15KMT2ATDP1GAA
SCHEMBL1349621 0.83 ALDH1A1 (0.52) ALDH1A1ALOX15KMT2ATDP1GAA
SCHEMBL900830 0.81 ALDH1A1 (0.68) ALDH1A1ALOX15KMT2ATDP1GAA
SCHEMBL11602789 0.81 ALDH1A1 (0.62) ALDH1A1ALOX15KMT2ATDP1GAA
SCHEMBL29723345 0.81 TSHR (0.53) ALDH1A1ALOX15KMT2ATDP1GAA
SCHEMBL12869575 0.81 AKR1C3 (0.55) ALDH1A1TDP1GAAMAPTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 165 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4003974-A1 NOVEL HETEROARYL-TRIAZOLE COMPOUNDS AS PESTICIDES Bayer Aktiengesellschaft (DE) 2022-06-01 EP claimed
WO-2021013720-A1 NOVEL HETEROARYL-TRIAZOLE COMPOUNDS AS PESTICIDES BAYER AKTIENGESELLSCHAFT (DE) 2021-01-28 WO claimed
US-20180240975-A1 Bi-Nuclear Main Group Metal Phosphorescent Emitter SIEMENS AKTIENGESELLSCHAFT (DE) 2018-08-23 US claimed
EP-3114190-B1 BI-NUCLEAR MAIN GROUP METAL PHOSPHORESCENT EMITTER SIEMENS AG (DE) 2018-06-06 EP claimed
CN-106459744-A Bi-nuclear main group metal phosphorescent emitter 西门子公司 2017-02-22 CN claimed
EP-3114190-A1 BI-NUCLEAR MAIN GROUP METAL PHOSPHORESCENT EMITTER Siemens Aktiengesellschaft (DE) 2017-01-11 EP claimed
WO-2015180901-A1 BI-NUCLEAR MAIN GROUP METAL PHOSPHORESCENT EMITTER SIEMENS AKTIENGESELLSCHAFT (DE) 2015-12-03 WO claimed
US-12570638-B2 Fused imidazole derivatives as AHR antagonists SAIL BIOMEDICINES, INC. (US) 2026-03-10 US disclosed
US-20250388604-A1 Compounds and Their Use as PDE4 Activators MIRONID LIMITED (GB) 2025-12-25 US disclosed
EP-4572762-A1 COMPOUNDS AND THEIR USE AS PDE4 ACTIVATORS Mironid Limited (GB) 2025-06-25 EP disclosed
EP-4143195-B1 IMIDAZOPYRIDAZINES AS MODULATORS OF IL-17 JANSSEN PHARMACEUTICA NV (BE) 2025-05-21 EP disclosed
WO-2025072539-A1 AMINO ACID COMPOUNDS WITH NITROGEN LINKERS AND USES THEREOF PLIANT THERAPEUTICS, INC. (US) 2025-04-03 WO disclosed
CN-116003309-B Hydrazide compound, preparation method and application thereof 深圳微芯生物科技股份有限公司 2025-03-04 CN disclosed
WO-2005103004-A1 2-PYRIDINYLCYCLOALKYLBENZAMIDE DERIVATIVES AND THEIR USE AS FUNGICIDES BAYER CROPSCIENCE SA (FR) 2005-11-03 WO disclosed
EP-1591442-A1 2-Pyridinycycloalkylbenzamide derivatives and their use as fungicides Bayer CropScience S.A. (FR) 2005-11-02 EP disclosed
WO-2005058828-A1 2-PYRIDINYLETHYLBENZAMIDE DERIVATIVES BAYER CROPSCIENCE S.A. (FR) 2005-06-30 WO disclosed
WO-2004103953-A1 DIFLUOROMETHYLBENZANILIDES AND USE THEREOF FOR COMBATING MICRO-ORGANISMS, INTERMEDIATE PRODUCTS AND USE THEREOF BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2004-12-02 WO disclosed
EP-0722430-B1 DIHALOPROPENE COMPOUNDS, INSECTICIDAL/ACARICIDAL AGENTS CONTAINING SAME, AND INTERMEDIATES FOR THEIR PRODUCTION SUMITOMO CHEMICAL CO (JP) 1998-10-21 EP disclosed
EP-0722430-A1 DIHALOPROPENE COMPOUNDS, INSECTICIDAL/ACARICIDAL AGENTS CONTAINING SAME, AND INTERMEDIATES FOR THEIR PRODUCTION SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1996-07-24 EP disclosed
WO-1996004228-A1 DIHALOPROPENE COMPOUNDS, INSECTICIDAL/ACARICIDAL AGENTS CONTAINING SAME, AND INTERMEDIATES FOR THEIR PRODUCTION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1996-02-15 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180240975-A1 Bi-Nuclear Main Group Metal Phosphorescent Emitter FOXM1, NUCB2, L3MBTL3 ALDH1A1 3139/4885ALOX15 2585/4885KMT2A 3989/4885
US-20250388604-A1 Compounds and Their Use as PDE4 Activators PDE4A, PDE7A, PDE4B ALDH1A1 989/4885ALOX15 3238/4885KMT2A 3462/4885
US-12570638-B2 Fused imidazole derivatives as AHR antagonists AHR, ARNT, AIPL1 ALDH1A1 1335/4885ALOX15 1849/4885KMT2A 377/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.