SCHEMBL4657785

SCHEMBL4657785

O=C(c1cccc([N+](=O)[O-])c1)C(Br)(Br)Br

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES2 O00748 1/20 0.70
CES1 P23141 1/20 0.70
TP53 P04637 1/20 0.68
ALDH1A1 P00352 5/20 0.66
TSHR P16473 4/20 0.66
KMT2A Q03164 6/20 0.58
MEN1 O00255 5/20 0.58
PRSS1 P07477 1/20 0.57
PRSS2 P07478 1/20 0.57
PRSS3 P35030 1/20 0.57
LMNA P02545 1/20 0.57
MAPT P10636 5/20 0.57
POLB P06746 3/20 0.57
BLM P54132 1/20 0.57
HTT P42858 3/20 0.54
CTDSP1 Q9GZU7 2/20 0.54
DDX3X O00571 1/20 0.54
RXFP1 Q9HBX9 1/20 0.54
ALOX15 P16050 1/20 0.53
RAB9A P51151 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7944841 0.86 ALDH1A1 (0.67) CES2CES1TP53ALDH1A1TSHR
SCHEMBL923488 0.86 CES2 (0.66) CES2CES1TP53ALDH1A1TSHR
SCHEMBL2199368 0.83 CES2 (0.72) CES2CES1TP53ALDH1A1TSHR
SCHEMBL28515318 0.83 ALDH1A1 (0.63) CES2CES1TP53ALDH1A1TSHR
SCHEMBL2156825 0.82 CES1 (1.00) CES2CES1TP53ALDH1A1TSHR
SCHEMBL181572 0.82 CES2 (0.78) CES2CES1TP53ALDH1A1TSHR
SCHEMBL31374765 0.82 CES1 (1.00) CES2CES1TP53ALDH1A1TSHR
SCHEMBL6678192 0.82 TP53 (0.63) CES2CES1TP53ALDH1A1TSHR
SCHEMBL2170995 0.81 CES2 (0.75) CES2CES1TP53ALDH1A1TSHR
SCHEMBL8962468 0.81 CES2 (0.75) CES2CES1TP53ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 144 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0003263-B1 A METHOD OF FORMING AN IMAGE, AND AN IMAGING ELEMENT FOR INHIBITING IMAGE FORMATION WITH COBALT (III) COMPLEXES EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1982-09-29 EP claimed
EP-0003263-A1 A method of forming an image, and an imaging element for inhibiting image formation with cobalt (III) complexes EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1979-08-08 EP claimed
WO-1979000448-A1 INHIBITING IMAGE FORMATION WITH COBALT(III)COMPLEXES EASTMAN KODAK CO (US) 1979-07-26 WO claimed
EP-4317361-A1 TEST TOOL AND TESTING METHOD FUJIFILM Corporation (JP) 2024-02-07 EP disclosed
US-20240016965-A1 ULTRAVIOLET-SENSING MEMBER AND ULTRAVIOLET-SENSING KIT FUJIFILM CORPORATION (JP) 2024-01-18 US disclosed
EP-4299690-A1 UV RADIATION SENSITIVE MEMBER AND UV RADIATION SENSITIVE KIT FUJIFILM Corporation (JP) 2024-01-03 EP disclosed
US-20230417658-A1 INSPECTION TOOL AND INSPECTION METHOD FUJIFILM CORPORATION (JP) 2023-12-28 US disclosed
US-20230392980-A1 ULTRAVIOLET-SENSING MEMBER, MICROCAPSULE, PRODUCTION METHOD OF MICROCAPSULE, DISPERSION LIQUID FOR FORMING ULTRAVIOLET-SENSING LAYER, AND ULTRAVIOLET-SENSING KIT FUJIFILM CORPORATION (JP) 2023-12-07 US disclosed
US-20230392981-A1 ULTRAVIOLET-SENSING MEMBER AND ULTRAVIOLET-SENSING KIT FUJIFILM CORPORATION (JP) 2023-12-07 US disclosed
WO-2023079992-A1 INSPECTION TOOL, AND INSPECTION METHOD 富士フイルム株式会社 2023-05-11 WO disclosed
WO-2022209858-A1 UV RADIATION SENSING MEMBER AND UV RADIATION SENSING KIT 富士フイルム株式会社 2022-10-06 WO disclosed
US-4251619-A Process for forming photo-polymeric image KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1981-02-17 US disclosed
US-4250247-A COMPRISING AN ACID-FORMING COMPOUND AND A COMPOUND HAVING AS AN ACID-CLEAVABLE GROUP AN N-ACYLIMINOCARBONATE; RELIEF IMAGES; OFFSET PRINTING HOECHST AKTIENGESELLSCHAFT (DE) 1981-02-10 US disclosed
US-4248957-A ENOL ETHER CONTAINING COMPOUND OF WHICH THE SOLUBILITY IN DEVELOPER INCREASES ON CLEAVAGE HOECHST AKTIENGESELLSCHAFT (DE) 1981-02-03 US disclosed
US-4247611-A ACETAL RESIN, ACID DONER HOECHST AKTIENGESELLSCHAFT (DE) 1981-01-27 US disclosed
EP-0006626-A2 Radiation-sensitive mixture and process for producing relief images HOECHST AKTIENGESELLSCHAFT (DE) 1980-01-09 EP disclosed
EP-0006627-A2 Radiation-sensitive mixture and process for producing relief images HOECHST AKTIENGESELLSCHAFT (DE) 1980-01-09 EP disclosed
WO-1979000448-A1 INHIBITING IMAGE FORMATION WITH COBALT(III)COMPLEXES EASTMAN KODAK CO (US) 1979-07-26 WO disclosed
US-4111692-A ALIPHATIC NITROGEN COMPOUND, HALOGEN COMPOUND AS FREE RADICAL GENERATOR TOYO BOSEKI KABUSHIKI KAISHA (JP) 1978-09-05 US disclosed
US-4101323-A Radiation-sensitive copying composition HOECHST AKTIENGESELLSCHAFT (DE) 1978-07-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240016965-A1 ULTRAVIOLET-SENSING MEMBER AND ULTRAVIOLET-SENSING KIT KIT, SARS1, UNG CES2 3243/4885CES1 2926/4885TP53 328/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.