Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.75 |
| ▸ | CES1 | P23141 | 1/20 | 0.75 |
| ▸ | TP53 | P04637 | 1/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.70 |
| ▸ | TSHR | P16473 | 4/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.62 |
| ▸ | MEN1 | O00255 | 4/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.61 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.61 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.61 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 4/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | BLM | P54132 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL181572 | 0.86 | CES2 (0.78) | CES2CES1TP53ALDH1A1TSHR | |
| SCHEMBL2156825 | 0.86 | CES1 (1.00) | CES2CES1TP53ALDH1A1TSHR | |
| SCHEMBL31374765 | 0.86 | CES1 (1.00) | CES2CES1TP53ALDH1A1TSHR | |
| SCHEMBL8962468 | 0.84 | CES2 (0.75) | CES2CES1TP53ALDH1A1TSHR | |
| SCHEMBL29490968 | 0.84 | TP53 (1.00) | CES2CES1TP53ALDH1A1TSHR | |
| SCHEMBL27709081 | 0.84 | TP53 (1.00) | CES2CES1TP53ALDH1A1TSHR | |
| SCHEMBL132618 | 0.84 | TP53 (1.00) | CES2CES1TP53ALDH1A1TSHR | |
| SCHEMBL4092998 | 0.83 | CES2 (0.74) | CES2CES1TP53ALDH1A1TSHR | |
| Bicarbonate SCHEMBL27282989 | 0.83 | TP53 (0.71) | CES2CES1TP53ALDH1A1TSHR | |
| Benzene SCHEMBL28121215 | 0.83 | TP53 (0.71) | CES2CES1TP53ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2697206-B1 | HETEROCYCLIC COMPOUNDS AND USES THEREOF IN THE TREATMENT OF SEXUAL DISORDERS | ATIR HOLDING S A (LU) | 2019-04-03 | — | — | EP | claimed |
| US-20160185743-A1 | 15-Oxospiramilactone Derivatives, Preparation Method and Uses Thereof | CENTER FOR EXCELLENCE IN MOLECULAR CELL SCIENCE, CHINESE ACADEMY OF SCIENCES (CN) | 2016-06-30 | — | — | US | claimed |
| US-20150322094-A1 | USE OF SUBSTITUTED 2,3-DIHYDRO-1-BENZOFURAN-4-CARBOXYLIC ACIDS OR SALTS THEREOF AS ACTIVE SUBSTANCES AGAINST ABIOTIC PLANT STRESS | BAYER CROPSCIENCE AG (DE) | 2015-11-12 | — | — | US | claimed |
| EP-2892343-A1 | USE OF SUBSTITUTED 2,3-DIHYDRO-1-BENZOFURAN-4-CARBOXYLIC ACIDS OR SALTS THEREOF AS ACTIVE SUBSTANCES AGAINST ABIOTIC PLANT STRESS | Bayer CropScience AG (DE) | 2015-07-15 | — | — | EP | claimed |
| WO-2014037349-A1 | USE OF SUBSTITUTED 2,3-DIHYDRO-1-BENZOFURAN-4-CARBOXYLIC ACIDS OR SALTS THEREOF AS ACTIVE SUBSTANCES AGAINST ABIOTIC PLANT STRESS | BAYER CROPSCIENCE AG (DE) | 2014-03-13 | — | — | WO | claimed |
| EP-0249999-A2 | Triazolyl ethyl ethers and fungicides containing them | BASF Aktiengesellschaft (DE) | 1987-12-23 | — | — | EP | claimed |
| CN-111479801-A | Compound and method for producing compound | 富士胶片株式会社 | 2020-07-31 | — | — | CN | disclosed |
| EP-2697206-B1 | HETEROCYCLIC COMPOUNDS AND USES THEREOF IN THE TREATMENT OF SEXUAL DISORDERS | ATIR HOLDING S A (LU) | 2019-04-03 | — | — | EP | disclosed |
| US-10112918-B2 | 15-oxospiramilactone derivatives, preparation method and uses thereof | KUNMING INSTITUTE OF BOTANY, THE CHINESE ACADEMY OF SCIENCES (CN) | 2018-10-30 | — | — | US | disclosed |
| US-10022454-B2 | Functionalized phosphorodiamites for therapeutic oligonucleotide synthesis | LIPOSCIENCES, LLC (US) | 2018-07-17 | — | — | US | disclosed |
| US-20170224832-A9 | SELF DELIVERING BIO-LABILE PHOSPHATE PROTECTED PRO-OLIGOS FOR OLIGONUCLEOTIDE BASED THERAPEUTICS AND MEDIATING RNA INTERFERENCE | PETERSEN SCOTT G (US) | 2017-08-10 | — | — | US | disclosed |
| EP-3067359-A1 | SELF DELIVERING BIO-LABILE PHOSPHATE PROTECTED PRO-OLIGOS FOR OLIGONUCLEOTIDE BASED THERAPEUTICS AND MEDIATING RNA INTERFERENCE | Petersen, Scott G. (US) | 2016-09-14 | — | — | EP | disclosed |
| US-20160185743-A1 | 15-Oxospiramilactone Derivatives, Preparation Method and Uses Thereof | CENTER FOR EXCELLENCE IN MOLECULAR CELL SCIENCE, CHINESE ACADEMY OF SCIENCES (CN) | 2016-06-30 | — | — | US | disclosed |
| US-20030004331-A1 | Method for purifying 5' -protected thymidines and novel derivatives thereof | MITSUI CHEMICALS, INC. (JP) | 2003-01-02 | — | — | US | disclosed |
| EP-1258489-A1 | Method for purifying 5'-protected thymidines | Mitsui Chemicals, Inc. (JP) | 2002-11-20 | — | — | EP | disclosed |
| US-6020426-A | BLOCK OR GRAFT COPOLYMER | FUJI XEROX CO., LTD. (JP) | 2000-02-01 | — | — | US | disclosed |
| US-5155113-A | Administering 5-fluorouracil and derivatives with pyridine and pyridone derivatives | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1992-10-13 | — | — | US | disclosed |
| EP-0249999-A2 | Triazolyl ethyl ethers and fungicides containing them | BASF Aktiengesellschaft (DE) | 1987-12-23 | — | — | EP | disclosed |
| EP-0180188-A2 | A composition for increasing the anti-cancer activity of an anti-cancer compound | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1986-05-07 | — | — | EP | disclosed |
| US-4239851-A | DISSOLVING AN OIL SOLUBLE ADDITIVE IN AN EPOXY COMPOUND | FUJI PHOTO FILM CO., LTD. (JP) | 1980-12-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030004331-A1 | Method for purifying 5' -protected thymidines and novel derivatives thereof | TYMP, TYMS, DUT | CES2 2859/4885CES1 2837/4885TP53 569/4885 |
| US-20160185743-A1 | 15-Oxospiramilactone Derivatives, Preparation Method and Uses Thereof | WNT1, WNT3, WNT3A | CES2 4376/4885CES1 1055/4885TP53 835/4885 |
| US-20150322094-A1 | USE OF SUBSTITUTED 2,3-DIHYDRO-1-BENZOFURAN-4-CARBOXYLIC ACIDS OR SALTS THEREOF AS ACTIVE SUBSTANCES AGAINST ABIOTIC PLANT STRESS | CAT, HSF1, HPD | CES2 1061/4885CES1 1114/4885TP53 3829/4885 |
| US-10022454-B2 | Functionalized phosphorodiamites for therapeutic oligonucleotide synthesis | NCL, PHOSPHO1, POLN | CES2 4245/4885CES1 3750/4885TP53 1169/4885 |
| US-10112918-B2 | 15-oxospiramilactone derivatives, preparation method and uses thereof | WNT1, WNT3, WNT3A | CES2 4376/4885CES1 1055/4885TP53 835/4885 |
| US-20170224832-A9 | SELF DELIVERING BIO-LABILE PHOSPHATE PROTECTED PRO-OLIGOS FOR OLIGONUCLEOTIDE BASED THERAPEUTICS AND MEDIATING RNA INTERFERENCE | POLN, SARNP, NCL | CES2 3708/4885CES1 3899/4885TP53 433/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.