SCHEMBL465815

SCHEMBL465815

C=C(C)C(=O)NCCN=C=O

nearest known ligand 0.32

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TGFBR1 P36897 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL33517 0.89 KEAP1 (0.40) TGFBR1
SCHEMBL465655 0.87 KEAP1 (0.42)
SCHEMBL19988824 0.86 KEAP1 (0.41)
SCHEMBL465638 0.80 TGFBR1 (0.33) TGFBR1
SCHEMBL404098 0.79
SCHEMBL19478068 0.78 TGFBR1 (0.34) TGFBR1
SCHEMBL316224 0.76 TGFBR1 (0.41) TGFBR1
SCHEMBL14865435 0.76 TGFBR1 (0.33) TGFBR1
SCHEMBL9078067 0.73 TGFBR1 (0.32) TGFBR1
SCHEMBL16706591 0.73 TGFBR1 (0.32) TGFBR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7157538-B2 Covalently-bound, hydrophilic coating compositions for surgical implants ALCON, INC. (CH) 2007-01-02 US claimed
US-7138471-B2 Hydrophilic biomedical compositions COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 2006-11-21 US claimed
US-20060036022-A1 Covalently-bound, hydrophilic coating compositions for surgical implants ALCON INC. (CH) 2006-02-16 US claimed
US-20050004255-A1 Hydrophilic biomedical compositions COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 2005-01-06 US claimed
US-6774197-B1 IN SITU ADDITION POLYMERIZATION OF MACROMOLECULAR MONOMERS CONTAINING AMINO- OR HYDROXYL FUNCTIONAL GROUPS; INTRAOCULAR LENSES COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANIZATION (AU) 2004-08-10 US claimed
CN-114921129-B Self-repairing high-refractive-index ink and preparation method and application thereof 武汉工程大学 2023-09-19 CN disclosed
CN-115010849-B Solvent-free high-refractive-index optical material and preparation method and application thereof 武汉工程大学 2023-07-18 CN disclosed
CN-115010849-A Solvent-free high-refractive-index optical material and preparation method and application thereof 武汉工程大学 2022-09-06 CN disclosed
CN-114921129-A Self-repairing high-refractive-index ink and preparation method and application thereof 武汉工程大学 2022-08-19 CN disclosed
US-10095144-B2 Toner and method for manufacturing the same CANON KABUSHIKI KAISHA (JP) 2018-10-09 US disclosed
US-9996018-B2 Toner and method for manufacturing the same CANON KABUSHIKI KAISHA (JP) 2018-06-12 US disclosed
US-9996018-B2 Toner and method for manufacturing the same CANON KABUSHIKI KAISHA (JP) 2018-06-12 US disclosed
EP-2345679-B1 METHOD FOR PRODUCING GRAFT COPOLYMER, GRAFT COPOLYMER OBTAINED BY THE METHOD, RUBBER COMPOSITION CONTAINING THE GRAFT COPOLYMER, AND TIRE BRIDGESTONE CORP (JP) 2016-04-27 EP disclosed
EP-2345679-A1 METHOD FOR PRODUCING GRAFT COPOLYMER, GRAFT COPOLYMER OBTAINED BY THE METHOD, RUBBER COMPOSITION CONTAINING THE GRAFT COPOLYMER, AND TIRE Bridgestone Corporation (JP) 2011-07-20 EP disclosed
US-7208012-B2 Covalently-bound, hydrophilic coating compositions for surgical implants ALCON, INC. (CH) 2007-04-24 US disclosed
US-20070043436-A1 COVALENTLY-BOUND, HYDROPHILIC COATING COMPOSITIONS FOR SURGICAL IMPLANTS ALCON, INC. (CH) 2007-02-22 US disclosed
US-7157538-B2 Covalently-bound, hydrophilic coating compositions for surgical implants ALCON, INC. (CH) 2007-01-02 US disclosed
WO-2006068852-A1 SOLVENT RESISTANT IMAGEABLE ELEMENT EASTMAN KODAK COMPANY (US) 2006-06-29 WO disclosed
US-20060036022-A1 Covalently-bound, hydrophilic coating compositions for surgical implants ALCON INC. (CH) 2006-02-16 US disclosed
US-6969579-B1 top layer containing a co-polymer of an unsaturated compound containing an imide group and a comonomer selected from an acryl imides, acrylonitriles, acryalmides and acrylic acids; chemical resistance printing plate EASTMAN KODAK COMPANY (US) 2005-11-29 US disclosed