Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 11/20 | 0.42 |
| ▸ | NFE2L2 | Q16236 | 11/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | PAOX | Q6QHF9 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19988824 | 0.98 | KEAP1 (0.41) | KEAP1NFE2L2KDM4EMAPK1HIF1A | |
| SCHEMBL33517 | 0.95 | KEAP1 (0.40) | KEAP1NFE2L2KDM4EMAPK1HIF1A | |
| SCHEMBL465815 | 0.87 | TGFBR1 (0.32) | — | |
| SCHEMBL907569 | 0.81 | KDM4E (0.52) | KDM4EMAPK1HIF1APAOXMEN1 | |
| SCHEMBL12265346 | 0.80 | KDM4E (0.61) | KEAP1NFE2L2KDM4EMAPK1HIF1A | |
| SCHEMBL13202339 | 0.80 | KDM4E (0.61) | KEAP1NFE2L2KDM4EMAPK1HIF1A | |
| SCHEMBL81704 | 0.79 | KEAP1 (0.58) | KEAP1NFE2L2 | |
| SCHEMBL59429 | 0.79 | KDM4E (0.56) | KDM4EMAPK1HIF1APAOXMEN1 | |
| SCHEMBL8775294 | 0.79 | KDM4E (0.56) | KDM4EMAPK1HIF1APAOXMEN1 | |
| SCHEMBL8775297 | 0.79 | KDM4E (0.56) | KDM4EMAPK1HIF1APAOXMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2345679-B1 | METHOD FOR PRODUCING GRAFT COPOLYMER, GRAFT COPOLYMER OBTAINED BY THE METHOD, RUBBER COMPOSITION CONTAINING THE GRAFT COPOLYMER, AND TIRE | BRIDGESTONE CORP (JP) | 2016-04-27 | — | — | EP | disclosed |
| EP-2345679-A1 | METHOD FOR PRODUCING GRAFT COPOLYMER, GRAFT COPOLYMER OBTAINED BY THE METHOD, RUBBER COMPOSITION CONTAINING THE GRAFT COPOLYMER, AND TIRE | Bridgestone Corporation (JP) | 2011-07-20 | — | — | EP | disclosed |