SCHEMBL4658253

SCHEMBL4658253

O=C(Cl)c1c(Br)c(Br)c(C(=O)Cl)c(Br)c1Br

nearest known ligand 0.39

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.39
PTPN1 P18031 2/20 0.36
GSK3B P49841 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10332292 0.97 ALDH1A1 (0.38) ALDH1A1PTPN1GSK3B
SCHEMBL11786595 0.94 ALDH1A1 (0.36) ALDH1A1PTPN1GSK3B
SCHEMBL11052757 0.93 ALDH1A1 (0.39) ALDH1A1PTPN1GSK3B
SCHEMBL9535859 0.90 ALDH1A1 (0.38) ALDH1A1PTPN1GSK3B
SCHEMBL10615599 0.82 ALDH1A1 (0.40) ALDH1A1PTPN1
SCHEMBL11701959 0.80 PTPN1 (0.40) PTPN1
SCHEMBL7530202 0.80 ALDH1A1 (0.32) ALDH1A1
SCHEMBL11819466 0.80 CA2 (0.40) ALDH1A1GSK3B
SCHEMBL8913308 0.76 ALDH1A1 (0.47) ALDH1A1
SCHEMBL11816572 0.76 CA1 (0.37) ALDH1A1PTPN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8511396-B2 Flame suppression agent, system and uses THE UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF THE NATIONAL AERONAUTICS AND SPACE ADMINISTRATION (US) 2013-08-20 US disclosed
US-20130075115-A1 Flame Suppression Agent, System and Uses SPACE ADMINISTRATION (US) 2013-03-28 US disclosed
EP-1395340-B1 FLAME SUPPRESSION AGENT, SYSTEM AND USES US HEALTH (US) 2008-12-10 EP disclosed
US-20040129435-A1 Flame suppression agent, system and uses NATIONAL AERONAUTICS AND SPACE ADMINISTRATION, U.S. GOVERNMENT AS REPRESENTED BY THE ADMINISTRATOR OF 2004-07-08 US disclosed
EP-1395340-A1 FLAME SUPPRESSION AGENT, SYSTEM AND USES The United States Of America, represented by The Administrator Of National Aeronautics And Space Administration (US) 2004-03-10 EP disclosed
WO-2002096519-A1 FLAME SUPPRESSION AGENT, SYSTEM AND USES NATIONAL AERONAUTICS AND SPACE ADMINISTRATION (US) 2002-12-05 WO disclosed
US-4564705-A POLYAMIDE, POLYUREA AND POLYURETHANE MONOMERS E. I. DU PONT DE NEMOURS AND COMPANY (US) 1986-01-14 US disclosed
US-4451642-A Bis(aminoneopentyl) aromatics and polyamides derived therefrom E. I. DU PONT DE NEMOURS AND COMPANY (US) 1984-05-29 US disclosed
EP-0031436-B1 A METHOD FOR THE CLEAVAGE OF SILOXANES HÜLS TROISDORF AKTIENGESELLSCHAFT (DE) 1984-02-15 EP disclosed
US-4310680-A METAL OR METAL COMPOUND CATALYST DYNAMIT NOBEL AG (DE) 1982-01-12 US disclosed
EP-0031436-A2 A method for the cleavage of siloxanes HÜLS TROISDORF AKTIENGESELLSCHAFT (DE) 1981-07-08 EP disclosed
US-4130579-A Bis(2-methyl-2-cyanopropyl) aromatics E. I. DU PONT DE NEMOURS AND COMPANY (US) 1978-12-19 US disclosed
US-4001179-A Bis-(tetrahalophthalimidocarbonyl)-benzene VELSICOL CHEMICAL CORPORATION (US) 1977-01-04 US disclosed
US-3974109-A FLAME RETARDANT FOAMS UNION CARBIDE CORPORATION (US) 1976-08-10 US disclosed