Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.33 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.33 |
| ▸ | SLC16A1 | P53985 | 1/20 | 0.33 |
| ▸ | MCTS1 | Q9ULC4 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 3/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.31 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.31 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.30 |
| ▸ | HTR6 | P50406 | 1/20 | 0.30 |
| ▸ | SLC1A5 | Q15758 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3842766 | 0.86 | ATM (0.33) | SMN1; SMN2ATMCXCR3BRD4HTR2C | |
| SCHEMBL1268407 | 0.85 | ATM (0.34) | SMN1; SMN2ATMBRD4 | |
| SCHEMBL4626768 | 0.74 | BRD4 (0.38) | SMN1; SMN2BRD4HTR2CKMT2APTGER1 | |
| SCHEMBL3840763 | 0.69 | BRAF (0.42) | CYP2C9 | |
| SCHEMBL1268133 | 0.67 | RIPK1 (0.39) | SMN1; SMN2ATMHTR2CSLC6A4KMT2A | |
| SCHEMBL1267213 | 0.66 | KCNH2 (0.34) | BRD4HTR6HTR2A | |
| SCHEMBL12252448 | 0.66 | NTRK1 (0.35) | BRD4HTR6 | |
| SCHEMBL1881855 | 0.66 | MMP1 (0.36) | TAS2R14HTR6HTR2A | |
| SCHEMBL16997458 | 0.65 | HTR6 (0.39) | HTR6HTR2AF2 | |
| SCHEMBL1266811 | 0.64 | BRD4 (0.40) | BRD4HTR2CHTR6HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008063888-A2 | COMPOUNDS MODULATING C-FMS AND/OR C-KIT ACTIVITY AND USES THEREFOR | PLEXXIKON, INC. (US) | 2008-05-29 | — | — | WO | disclosed |