Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.60 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.60 |
| ▸ | SENP1 | Q9P0U3 | 2/20 | 0.55 |
| ▸ | FNTA | P49354 | 1/20 | 0.54 |
| ▸ | FNTB | P49356 | 1/20 | 0.54 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.48 |
| ▸ | ESR1 | P03372 | 3/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | SHBG | P04278 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.46 |
| ▸ | USP5 | P45974 | 1/20 | 0.46 |
| ▸ | USP4 | Q13107 | 1/20 | 0.46 |
| ▸ | IDO1 | P14902 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4789964 | 0.90 | CA2 (0.53) | CA2CAMK2ASENP1FNTAFNTB | |
| SCHEMBL4659000 | 0.87 | CA2 (0.52) | CA2CAMK2ASENP1FNTAFNTB | |
| SCHEMBL6558102 | 0.84 | CA2 (0.58) | CA2CAMK2ASENP1FNTAFNTB | |
| SCHEMBL112488 | 0.82 | CYP4F2 (0.66) | CA2CAMK2ASENP1FNTAFNTB | |
| SCHEMBL16066069 | 0.82 | CA2 (0.59) | CA2CAMK2ASENP1FNTAFNTB | |
| SCHEMBL414384 | 0.80 | SENP1 (0.59) | CA2CAMK2ASENP1FNTAFNTB | |
| Hydrochloric Acid SCHEMBL27517466 | 0.80 | CYP4F2 (0.63) | CA2CAMK2ASENP1FNTAFNTB | |
| SCHEMBL7646563 | 0.80 | CYP4F2 (0.63) | CA2CAMK2ASENP1FNTAFNTB | |
| SCHEMBL12715363 | 0.80 | SENP1 (0.43) | CA2CAMK2ASENP1ALDH1A1MAPK1 | |
| SCHEMBL8855417 | 0.79 | POLB (0.56) | CTBP2NPC1RAB9AALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190214145-A1 | Method and systems for creating and screening patient metabolite profile to diagnose current medical condition, diagnose current treatment state and recommend new treatment regimen | KUREK ITZHAK (US) | 2019-07-11 | — | — | US | disclosed |
| EP-1739114-B1 | POLYIMIDE RESIN, MULTILAYER FILM, MULTILAYER FILM WITH METAL LAYER, AND SEMICONDUCTOR DEVICE | TORAY INDUSTRIES (JP) | 2008-12-17 | — | — | EP | disclosed |
| US-20070260035-A1 | Polyimide Resin, Laminate Film, Metal Layer-Bearing Laminate Film, and Semiconductor Device | TORAY INDUSTRIES, INC. (JP) | 2007-11-08 | — | — | US | disclosed |
| US-7183279-B2 | Histogranin-like peptides and non-peptides, processes for their preparation and uses thereof | UNIVERSITY OF OTTAWA (CA) | 2007-02-27 | — | — | US | disclosed |
| EP-1739114-A1 | POLYIMIDE RESIN, MULTILAYER FILM, MULTILAYER FILM WITH METAL LAYER, AND SEMICONDUCTOR DEVICE | TORAY INDUSTRIES, INC. (JP) | 2007-01-03 | — | — | EP | disclosed |
| US-20060252673-A1 | Histogranin-like peptides and non-peptides, processes for their preparation and uses thereof | UNIVERSITY OF OTTAWA (CA) | 2006-11-09 | — | — | US | disclosed |
| US-7074786-B2 | Histogranin-like peptides, processes for their preparation and uses thereof | UNIVERSITY OF OTTAWA (CA) | 2006-07-11 | — | — | US | disclosed |
| EP-1481002-B1 | HISTOGRANIN-LIKE PEPTIDES AND NON-PEPTIDES, PROCESSES FOR THEIR PREPARATION AND USES THEREOF | UNIV OTTAWA (CA) | 2006-04-19 | — | — | EP | disclosed |
| US-6972281-B2 | Histogranin-like peptides and non-peptides, processes for their preparation and uses thereof | UNIVERSITY OF OTTAWA (CA) | 2005-12-06 | — | — | US | disclosed |
| US-20050233953-A1 | Histogranin-like peptides, processes for their preparation and uses thereof | UNIVERSITY OF OTTAWA (CA) | 2005-10-20 | — | — | US | disclosed |
| EP-1481002-A1 | HISTOGRANIN-LIKE PEPTIDES AND NON-PEPTIDES, PROCESSES FOR THEIR PREPARATION AND USES THEREOF | University of Ottawa (CA) | 2004-12-01 | — | — | EP | disclosed |
| US-20030176329-A1 | Histogranin-like peptides and non-peptides, processes for their preparation and uses thereof | OTTAWA, UNIVERSITY OF (CA) | 2003-09-18 | — | — | US | disclosed |
| WO-2003066673-A1 | HISTOGRANIN-LIKE PEPTIDES AND NON-PEPTIDES, PROCESSES FOR THEIR PREPARATION AND USES THEREOF | UNIVERSITY OF OTTAWA (CA) | 2003-08-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060252673-A1 | Histogranin-like peptides and non-peptides, processes for their preparation and uses thereof | GRPR, HRH2, OPRL1 | CA2 446/4885CAMK2A 3208/4885SENP1 1684/4885 |
| US-20030176329-A1 | Histogranin-like peptides and non-peptides, processes for their preparation and uses thereof | GRPR, OPRL1, NGLY1 | CA2 268/4885CAMK2A 2350/4885SENP1 1375/4885 |
| US-20050233953-A1 | Histogranin-like peptides, processes for their preparation and uses thereof | GRPR, HRH2, OPRL1 | CA2 459/4885CAMK2A 3329/4885SENP1 1513/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.