Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 15/20 | 0.46 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4660425 | 0.79 | FAAH (0.56) | FAAH | |
| SCHEMBL4189326 | 0.77 | FAAH (0.72) | FAAH | |
| SCHEMBL4184172 | 0.76 | FAAH (0.74) | FAAH | |
| SCHEMBL4659049 | 0.73 | FAAH (0.62) | FAAH | |
| SCHEMBL4659119 | 0.70 | FAAH (0.56) | FAAH | |
| SCHEMBL4724280 | 0.70 | FAAH (0.57) | FAAH | |
| SCHEMBL4659075 | 0.67 | FAAH (0.44) | FAAH | |
| SCHEMBL4658122 | 0.67 | FAAH (0.47) | FAAH | |
| SCHEMBL4184168 | 0.63 | FAAH (1.00) | FAAH | |
| SCHEMBL4195962 | 0.63 | FAAH (1.00) | FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1954137-A4 | 2-KETO-OXAZOLES AS MODULATORS OF FATTY ACID AMIDE HYDROLASE | JANSSEN PHARMACEUTICA NV (BE) | 2008-12-17 | — | — | EP | claimed |
| EP-1954137-A2 | 2-KETO-OXAZOLES AS MODULATORS OF FATTY ACID AMIDE HYDROLASE | JANSSEN PHARMACEUTICA N.V. (BE) | 2008-08-13 | — | — | EP | claimed |
| WO-2007061862-A2 | 2-KETO-OXAZOLES AS MODULATORS OF FATTY ACID AMIDE HYDROLASE | JANSSEN PHARMACEUTICA N.V. (BE) | 2007-05-31 | — | — | WO | claimed |