Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | CFTR | P13569 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPK9 | P45984 | 4/20 | 0.38 |
| ▸ | MAPK10 | P53779 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | MAPK3 | P27361 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | PTK2 | Q05397 | 2/20 | 0.36 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.36 |
| ▸ | PLK1 | P53350 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL70873 | 0.78 | CFTR (0.50) | GAACFTRALDH1A1LMNAKDM4E | |
| SCHEMBL10428536 | 0.75 | NOTUM (0.46) | ALDH1A1KDM4E | |
| SCHEMBL23772062 | 0.74 | CREBBP (0.36) | GAACFTRKDM4E | |
| SCHEMBL20885320 | 0.74 | BRD4 (0.41) | GAACFTRALDH1A1LMNAKDM4E | |
| SCHEMBL1267035 | 0.73 | GAA (0.70) | GAALMNARXFP1PLK1 | |
| SCHEMBL30745167 | 0.73 | GAA (0.70) | GAALMNARXFP1PLK1 | |
| SCHEMBL14067041 | 0.72 | CFTR (0.42) | GAACFTRALDH1A1MAPK9MAPK10 | |
| SCHEMBL13407881 | 0.70 | GAA (0.46) | GAACFTRALDH1A1LMNAKDM4E | |
| SCHEMBL2185981 | 0.70 | KDM4E (0.53) | ALDH1A1LMNAKDM4E | |
| SCHEMBL4114660 | 0.69 | ALDH1A1 (0.39) | GAACFTRALDH1A1MAPK9MAPK10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1916894-A1 | SYNERGISTIC FUNGICIDAL ACTIVE SUBSTANCE COMBINATIONS CONTAINING A CARBOXAMIDE, AN AZOLE, A SECOND AZOLE OR A STROBILURINE | Bayer CropScience Aktiengesellschaft (DE) | 2008-05-07 | — | — | EP | disclosed |
| WO-2007031141-A1 | SYNERGISTIC FUNGICIDAL ACTIVE SUBSTANCE COMBINATIONS CONTAINING A CARBOXAMIDE, AN AZOLE, A SECOND AZOLE OR A STROBILURINE | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2007-03-22 | — | — | WO | disclosed |