Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Glyphosate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.34 |
| ▸ | BLM | P54132 | 4/20 | 0.34 |
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | ANPEP | P15144 | 1/20 | 0.33 |
| ▸ | GABRR3 | A8MPY1 | 1/20 | 0.33 |
| ▸ | GABRP | O00591 | 1/20 | 0.33 |
| ▸ | GABRD | O14764 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Glyphosate SCHEMBL2293917 | 0.92 | LMNA (0.37) | LMNABLMTSHRKMT2AALDH1A1 | |
| Glyphosate SCHEMBL612618 | 0.88 | GLRA1 (0.43) | LMNABLMTSHRKMT2AALDH1A1 | |
| Glyphosate SCHEMBL6056320 | 0.87 | MEN1 (0.40) | LMNABLMTSHRKMT2AMEN1 | |
| Glyphosate SCHEMBL29694166 | 0.87 | LMNA (0.43) | LMNABLMTSHRKMT2AMEN1 | |
| Glyphosate SCHEMBL214438 | 0.87 | LMNA (0.43) | LMNABLMTSHRKMT2AMEN1 | |
| Glyphosate SCHEMBL16440 | 0.87 | LMNA (0.43) | LMNABLMTSHRKMT2AMEN1 | |
| Glyphosate SCHEMBL1964442 | 0.87 | LMNA (0.43) | LMNABLMTSHRKMT2AMEN1 | |
| Glyphosate SCHEMBL30579950 | 0.87 | LMNA (0.43) | LMNABLMTSHRKMT2AMEN1 | |
| Glyphosate SCHEMBL30579951 | 0.87 | LMNA (0.43) | LMNABLMTSHRKMT2AMEN1 | |
| Glyphosate SCHEMBL8515704 | 0.87 | LMNA (0.43) | LMNABLMTSHRKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 226 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114423287-B | Stable herbicide composition comprising amine oxide and tertiary amine | 罗地亚经营管理公司 | 2024-06-14 | — | — | CN | claimed |
| CN-114096154-B | Stable herbicide composition comprising amine oxide and betaine | 罗地亚经营管理公司 | 2024-05-28 | — | — | CN | claimed |
| CN-113056196-B | Compositions comprising picolinate herbicides with glyphosate or glufosinate | 科迪华农业科技有限责任公司 | 2024-04-02 | — | — | CN | claimed |
| WO-2023228935-A1 | HERBICIDE COMPOSITION AND WEED CONTROLLING METHOD | 住友化学株式会社 | 2023-11-30 | — | — | WO | claimed |
| US-11399544-B2 | Glyphosate composition for dicamba tank mixtures with improved volatility | MONSANTO TECHNOLOGY LLC (US) | 2022-08-02 | — | — | US | claimed |
| WO-2022138632-A1 | HERBICIDE COMPOSITION AND WEED CONTROLLING METHOD | 住友化学株式会社 | 2022-06-30 | — | — | WO | claimed |
| CN-106386848-B | Herbicidal formulations comprising glyphosate and alkoxylated glycerides | 阿克苏诺贝尔化学品国际有限公司 | 2022-01-11 | — | — | CN | claimed |
| US-20210400967-A1 | COMPOSITIONS COMPRISING PYRIDINE CARBOXYLATE HERBICIDES WITH GLYPHOSATE OR GLUFOSINATE | CORTEVA AGRISCIENCE LLC (US) | 2021-12-30 | — | — | US | claimed |
| WO-2021052094-A1 | STABLE HERBICIDAL COMPOSITIONS COMPRISING AMINE OXIDE AND TERTIARY AMINE | RHODIA OPERATIONS (FR) | 2021-03-25 | — | — | WO | claimed |
| WO-2021039893-A1 | HERBICIDAL AGENT COMPOSITION AND WEED CONTROL METHOD | 住友化学株式会社 | 2021-03-04 | — | — | WO | claimed |
| EP-1617720-A1 | HERBICIDAL COMPOSITIONS CONTAINING GLYPHOSATE AND A PYRIDINE ANALOG | Monsanto Technology LLC (US) | 2006-01-25 | — | — | EP | claimed |
| US-20050026781-A1 | Antigrowth agents; controlling cell proliferation; synergistic mixture; concentrate for applying to leaves of plants | MONSANTO TECHNOLOGY LLC | 2005-02-03 | — | — | US | claimed |
| WO-2004093546-A1 | HERBICIDAL COMPOSITIONS CONTAINING GLYPHOSATE AND A PYRIDINE ANALOG | MONSANTO TECHNOLOGY LLC (US) | 2004-11-04 | — | — | WO | claimed |
| EP-1343375-A2 | AQUEOUS PESTICIDE FORMULATIONS AND NOVEL SURFACTANTS | Monsanto Technology LLC (US) | 2003-09-17 | — | — | EP | claimed |
| US-20030104943-A1 | Novel surfactants and formulations | MONSANTO TECHNOLOGY LLC | 2003-06-05 | — | — | US | claimed |
| WO-2002021924-A2 | HERBICIDAL COMPOSITIONS CONTAINING GLYPHOSATE AND BIPYRIDILIUM | MONSANTO TECHNOLOGY LLC (US) | 2002-03-21 | — | — | WO | claimed |
| WO-2001089302-A2 | AQUEOUS PESTICIDE FORMULATIONS AND NOVEL SURFACTANTS | MONSANTO TECHNOLOGY, LLC (US) | 2001-11-29 | — | — | WO | claimed |
| EP-1065934-A1 | COMBINATION OF GLYPHOSATE AND A TRIAZOLINONE HERBICIDE | MONSANTO COMPANY (US) | 2001-01-10 | — | — | EP | claimed |
| US-6127318-A | POSTEMERGENT HERBICIDE MIXTURE ALLOWS RAPID UPTAKE BY THE TARGET PLANT, EARLY VISUAL SYMPTOMS OF PLANT TREATMENT, AND CONTROL OF A BROAD SPECTRUM OF WEED SPECIES | MONSANTO COMPANY (US) | 2000-10-03 | — | — | US | claimed |
| WO-1999051099-A1 | COMBINATION OF GLYPHOSATE AND A TRIAZOLINONE HERBICIDE | MONSANTO COMPANY (US) | 1999-10-14 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11399544-B2 | Glyphosate composition for dicamba tank mixtures with improved volatility | PHOSPHO1, GDA, GYPA | LMNA 1086/4885BLM 923/4885TSHR 4212/4885 |
| US-20050026781-A1 | Antigrowth agents; controlling cell proliferation; synergistic mixture; concentrate for applying to leaves of plants | MKI67, CDC25C, CCNC | LMNA 2078/4885BLM 3576/4885TSHR 2748/4885 |
| US-20030104943-A1 | Novel surfactants and formulations | PHOSPHO1, GNMT, DDT | LMNA 1966/4885BLM 500/4885TSHR 4504/4885 |
| US-20210400967-A1 | COMPOSITIONS COMPRISING PYRIDINE CARBOXYLATE HERBICIDES WITH GLYPHOSATE OR GLUFOSINATE | GLUL, ASNS, PNPO | LMNA 4422/4885BLM 2993/4885TSHR 3585/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.