Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDPK1 | O15530 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 3/20 | 0.42 |
| ▸ | PPARA | Q07869 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.38 |
| ▸ | MMP12 | P39900 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4661314 | 0.85 | PDPK1 (0.39) | PDPK1PPARGPPARATSHRMEN1 | |
| SCHEMBL4661293 | 0.84 | MMP12 (0.46) | PDPK1PPARGPPARAMEN1LMNA | |
| SCHEMBL4661333 | 0.82 | LMNA (0.39) | PDPK1PPARGPPARATSHRMEN1 | |
| SCHEMBL4661136 | 0.79 | PPARA (0.42) | PPARGPPARAALDH1A1MMP12MGLL | |
| SCHEMBL10419234 | 0.78 | PPARA (0.57) | PDPK1PPARGPPARATSHRSLC6A2 | |
| SCHEMBL20360646 | 0.74 | TSHR (0.46) | TSHRMEN1LMNAKMT2ASLC6A2 | |
| SCHEMBL25034530 | 0.74 | TSHR (0.49) | TSHRMEN1LMNAKMT2ASLC6A2 | |
| SCHEMBL16395692 | 0.73 | TSHR (0.45) | TSHRMEN1LMNAKMT2ASLC6A2 | |
| SCHEMBL16673087 | 0.73 | PRKCA (0.51) | TSHRMEN1LMNAKMT2ASLC6A2 | |
| SCHEMBL20360292 | 0.73 | TSHR (0.45) | TSHRMEN1LMNAKMT2ASLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1627866-B1 | CARBOXYLIC ACID COMPOUND AND MEDICINE CONTAINING THE SAME | KOWA CO (JP) | 2008-12-24 | — | — | EP | disclosed |
| CN-100368374-C | Carboxylic compound and medicine comprising the same | KOWA CO (JP) | 2008-02-13 | — | — | CN | disclosed |
| US-7109242-B2 | Carboxylic compound and medicine comprising the same | KOWA COMPANY, LTD. (JP) | 2006-09-19 | — | — | US | disclosed |
| CN-1795163-A | Carboxylic compound and medicine comprising the same | KOWA CO (JP) | 2006-06-28 | — | — | CN | disclosed |
| EP-1627866-A1 | CARBOXYLIC ACID COMPOUND AND MEDICINE CONTAINING THE SAME | Kowa Company Ltd. (JP) | 2006-02-22 | — | — | EP | disclosed |