Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP12 | P39900 | 2/20 | 0.46 |
| ▸ | PPARA | Q07869 | 5/20 | 0.39 |
| ▸ | PPARG | P37231 | 4/20 | 0.39 |
| ▸ | DPP4 | P27487 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.37 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | THRA | P10827 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4661136 | 0.95 | PPARA (0.42) | MMP12PPARAPPARGGAAKDM4E | |
| SCHEMBL4659900 | 0.84 | PDPK1 (0.43) | MMP12PPARAPPARGALDH1A1MEN1 | |
| SCHEMBL4661257 | 0.80 | MMP12 (0.40) | MMP12PPARAPPARGDPP4GAA | |
| SCHEMBL4661420 | 0.77 | KCNH2 (0.34) | PPARAPPARGDPP4MEN1KMT2A | |
| SCHEMBL4659861 | 0.75 | HDAC3 (0.38) | MMP12PPARAPPARGGAAALDH1A1 | |
| SCHEMBL4659970 | 0.74 | HTR1A (0.40) | PPARAPPARGDPP4HDAC3HDAC4 | |
| SCHEMBL11622013 | 0.74 | PRKCA (0.43) | — | |
| SCHEMBL10420424 | 0.73 | PPARA (0.60) | MMP12PPARAPPARGHDAC3HDAC4 | |
| SCHEMBL4661332 | 0.72 | KCNH2 (0.40) | PPARAPPARGGAATHRATHRB | |
| SCHEMBL7279889 | 0.72 | MMP12 (0.68) | MMP12ALDH1A1MEN1HTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100261933-A1 | METHOD FOR PREPARING CARBOXYLIC ACID COMPOUND | KOWA COMPANY, LTD. (JP) | 2010-10-14 | — | — | US | disclosed |
| US-20100261933-A1 | METHOD FOR PREPARING CARBOXYLIC ACID COMPOUND | KOWA COMPANY, LTD. (JP) | 2010-10-14 | — | — | US | disclosed |
| EP-1627866-B1 | CARBOXYLIC ACID COMPOUND AND MEDICINE CONTAINING THE SAME | KOWA CO (JP) | 2008-12-24 | — | — | EP | disclosed |
| EP-2003112-A1 | METHOD FOR PRODUCING CARBOXYLIC ACID COMPOUND | Kowa Company, Ltd. (JP) | 2008-12-17 | — | — | EP | disclosed |
| US-7109242-B2 | Carboxylic compound and medicine comprising the same | KOWA COMPANY, LTD. (JP) | 2006-09-19 | — | — | US | disclosed |
| EP-1627866-A1 | CARBOXYLIC ACID COMPOUND AND MEDICINE CONTAINING THE SAME | Kowa Company Ltd. (JP) | 2006-02-22 | — | — | EP | disclosed |
| US-20050009909-A1 | Carboxylic compound and medicine comprising the same | KOWA COMPANY, LTD. (JP) | 2005-01-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050009909-A1 | Carboxylic compound and medicine comprising the same | CPT1A, GPR119, PNLIP | MMP12 1024/4885PPARA 68/4885PPARG 65/4885 |
| US-20100261933-A1 | METHOD FOR PREPARING CARBOXYLIC ACID COMPOUND | HCAR1, HAO1, HCAR2 | MMP12 3990/4885PPARA 310/4885PPARG 245/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.