Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VDR | P11473 | 12/20 | 0.80 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.78 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.78 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.78 |
| ▸ | PGR | P06401 | 2/20 | 0.78 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.78 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.78 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.78 |
| ▸ | HTR1A | P08908 | 1/20 | 0.78 |
| ▸ | MAPT | P10636 | 2/20 | 0.71 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.71 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.71 |
| ▸ | GC | P02774 | 1/20 | 0.71 |
| ▸ | RXRA | P19793 | 1/20 | 0.71 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.71 |
| ▸ | CNR1 | P21554 | 1/20 | 0.71 |
| ▸ | HTR2C | P28335 | 1/20 | 0.71 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.71 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.71 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ercalcitriol SCHEMBL12922723 | 1.00 | VDR (0.80) | VDRADORA3SLC6A2NR1I2PGR | |
| Ercalcitriol SCHEMBL17274136 | 1.00 | VDR (0.80) | VDRADORA3SLC6A2NR1I2PGR | |
| Ercalcitriol SCHEMBL4393978 | 1.00 | VDR (0.80) | VDRADORA3SLC6A2NR1I2PGR | |
| Ercalcitriol SCHEMBL264876 | 1.00 | VDR (0.80) | VDRADORA3SLC6A2NR1I2PGR | |
| Ercalcitriol SCHEMBL264875 | 1.00 | VDR (0.80) | VDRADORA3SLC6A2NR1I2PGR | |
| Ercalcitriol SCHEMBL4398182 | 1.00 | VDR (0.80) | VDRADORA3SLC6A2NR1I2PGR | |
| Ercalcitriol SCHEMBL23142603 | 1.00 | VDR (0.80) | VDRADORA3SLC6A2NR1I2PGR | |
| Ercalcitriol SCHEMBL8776000 | 1.00 | VDR (0.80) | VDRADORA3SLC6A2NR1I2PGR | |
| Ercalcitriol SCHEMBL9050396 | 1.00 | VDR (0.80) | VDRADORA3SLC6A2NR1I2PGR | |
| Ercalcitriol SCHEMBL21433255 | 1.00 | VDR (0.80) | VDRADORA3SLC6A2NR1I2PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 72 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080038374-A1 | New Use | LIPOPEPTIDE AB (SE) | 2008-02-14 | — | — | US | claimed |
| EP-1781302-A1 | NEW USE | Lipopeptide AB (SE) | 2007-05-09 | — | — | EP | claimed |
| US-20060281813-A1 | Methods of treating hyperproliferative cell disorders | RUBIN CHARLES | 2006-12-14 | — | — | US | claimed |
| EP-1628631-A2 | METHODS OF TREATING HYPERPROLIFERATIVE CELL DISORDERS | Achkar, Charles C. (US) | 2006-03-01 | — | — | EP | claimed |
| WO-2006011849-A1 | NEW USE | LIPOPEPTIDE AB (SE) | 2006-02-02 | — | — | WO | claimed |
| EP-1104294-B1 | COMPOSITIONS AND METHODS OF TREATING ABNORMAL CELL PROLIFERATION | LEO PHARMA A S (DK) | 2005-09-28 | — | — | EP | claimed |
| WO-2005000230-A2 | METHODS OF TREATING HYPERPROLIFERATIVE CELL DISORDERS | ACHKAR CHARLES (US) | 2005-01-06 | — | — | WO | claimed |
| US-6552009-B2 | Vitamin D analog and a retinoid, wherein: the retinoid is 4-oxo-retinol, 4-oxo- retinal, or 4-oxo-retinyl ester; also restoring the natural color of gray hair; treating hair and skin disorders | GENTRIX LLC | 2003-04-22 | — | — | US | claimed |
| US-20010049365-A1 | Vitamin D analog and a retinoid, wherein: the retinoid is 4-oxo-retinol, 4-oxo- retinal, or 4-oxo-retinyl ester; also restoring the natural color of gray hair; treating hair and skin disorders | LEO PHARMACEUTICAL PRODUCTS LTD. A/S (DK) | 2001-12-06 | — | — | US | claimed |
| US-6242435-B1 | VITAMIN D ANALOG AND A RETINOID | GENTRIX LLC | 2001-06-05 | — | — | US | claimed |
| US-20010002396-A1 | COMPOSITIONS AND METHODS OF TREATING SKIN CONDITIONS | GENTRIX LLC | 2001-05-31 | — | — | US | claimed |
| US-4225596-A | Method for treating calcium imbalance and improving calcium absorption in mammals | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 1980-09-30 | — | — | US | claimed |
| EP-4065592-B1 | COCRYSTALS OF STEROID AND SECOSTEROID COMPOUNDS AND COMPOSITIONS COMPRISING THEM | CENTER FOR INTELLIGENT RES IN CRYSTAL ENGINEERING S L (ES) | 2024-01-10 | — | — | EP | disclosed |
| US-20230251277-A1 | METHOD FOR DETERMINING THE LEVEL OF VITAMIN D AND METABOLITES THEREOF | ROCHE DIAGNOSTICS OPERATIONS, INC. | 2023-08-10 | — | — | US | disclosed |
| US-20230001012-A1 | COCRYSTALS OF STEROID AND SECOSTEROID COMPOUNDS AND COMPOSITIONS COMPRISING THEM | CENTER FOR INTELLIGENT RESEARCH IN CRYSTAL ENGINEERING, S.L. (ES) | 2023-01-05 | — | — | US | disclosed |
| EP-4065592-A1 | COCRYSTALS OF STEROID AND SECOSTEROID COMPOUNDS AND COMPOSITIONS COMPRISING THEM | Center for Intelligent Research in Crystal Engineering, S.L. (ES) | 2022-10-05 | — | — | EP | disclosed |
| US-4307231-A | Vitamin D-lactone derivative and process for preparing same | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 1981-12-22 | — | — | US | disclosed |
| US-4225596-A | Method for treating calcium imbalance and improving calcium absorption in mammals | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 1980-09-30 | — | — | US | disclosed |
| US-3880894-A | 1,25-Dihydroxyergocalciferol | WISCONSIN ALUMNI RES FOUND | 1975-04-29 | — | — | US | disclosed |
| US-3880894-A | 1,25-Dihydroxyergocalciferol | WISCONSIN ALUMNI RES FOUND | 1975-04-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010049365-A1 | Vitamin D analog and a retinoid, wherein: the retinoid is 4-oxo-retinol, 4-oxo- retinal, or 4-oxo-retinyl ester; also restoring the natural color of gray hair; treating hair and skin disorders | RBP4, VDR, CYP24A1 | VDR 2/4885ADORA3 430/4885SLC6A2 4566/4885 |
| US-20060281813-A1 | Methods of treating hyperproliferative cell disorders | HRAS, CDC73, MKI67 | VDR 14/4885ADORA3 4103/4885SLC6A2 4332/4885 |
| US-20230001012-A1 | COCRYSTALS OF STEROID AND SECOSTEROID COMPOUNDS AND COMPOSITIONS COMPRISING THEM | HSD3B1, HSD3B2, NR3C2 | VDR 234/4885ADORA3 3162/4885SLC6A2 1144/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.