Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 5/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.37 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9330478 | 0.86 | PIN1 (0.48) | KDM1AALDH1A1KDM4EPIN1MEN1 | |
| SCHEMBL2818996 | 0.82 | PDE10A (0.49) | ALDH1A1KDM4EMEN1KMT2AATM | |
| SCHEMBL4660259 | 0.72 | KDM1A (0.43) | KDM1AALDH1A1KDM4EPIN1MEN1 | |
| SCHEMBL5957199 | 0.69 | ALDH1A1 (0.64) | ALDH1A1KDM4EMEN1KMT2ARXFP1 | |
| SCHEMBL29392214 | 0.69 | NQO2 (0.50) | KDM1AALDH1A1KDM4EPIN1MEN1 | |
| SCHEMBL1996329 | 0.69 | NQO2 (0.50) | KDM1AALDH1A1KDM4EPIN1MEN1 | |
| Water SCHEMBL2991911 | 0.67 | PDE10A (0.63) | ALDH1A1KDM4EMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL9682802 | 0.66 | KMT2A (0.51) | KDM1AALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL17742243 | 0.66 | ALDH1A1 (0.61) | KDM1AALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL8875118 | 0.66 | SMN1; SMN2 (0.41) | ALDH1A1KDM4EMEN1KMT2AATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2004628-A2 | ACRIDINE DERIVATIVES WITH ANTITUMORAL ACTIVITY | Universidade Federal de Pernambuco-Ufpe (BR) | 2008-12-24 | — | — | EP | disclosed |
| WO-2007109871-A2 | ACRIDINE DERIVATIVES WITH ANTITUMORAL ACTIVITY | UNIVERSIDADE FEDERAL DE PERNAMBUCO - UFPE (BR) | 2007-10-04 | — | — | WO | disclosed |