Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | ALB | P02768 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.38 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3704563 | 0.83 | KDM4E (0.54) | RAB9AKDM4EALDH1A1LMNAKMT2A | |
| SCHEMBL2818992 | 0.83 | KDM4E (0.54) | RAB9AKDM4EALDH1A1LMNAKMT2A | |
| SCHEMBL9330478 | 0.76 | PIN1 (0.48) | KDM1AKDM4EALDH1A1LMNAPIN1 | |
| SCHEMBL4660256 | 0.72 | KDM1A (0.44) | KDM1ARAB9AKDM4EALDH1A1LMNA | |
| SCHEMBL4668561 | 0.71 | CA1 (0.51) | KDM4EALDH1A1LMNAPIN1MEN1 | |
| SCHEMBL4668564 | 0.71 | CA1 (0.51) | KDM4EALDH1A1LMNAPIN1MEN1 | |
| SCHEMBL6852607 | 0.71 | HCAR2 (0.60) | KDM4EALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL6852611 | 0.71 | HCAR2 (0.60) | KDM4EALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL8854345 | 0.70 | CYP2D6 (0.58) | RAB9AKDM4EALDH1A1LMNAMEN1 | |
| SCHEMBL6072850 | 0.70 | MIF (0.41) | KDM4EALDH1A1LMNAPIN1CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2004628-A2 | ACRIDINE DERIVATIVES WITH ANTITUMORAL ACTIVITY | Universidade Federal de Pernambuco-Ufpe (BR) | 2008-12-24 | — | — | EP | disclosed |
| WO-2007109871-A2 | ACRIDINE DERIVATIVES WITH ANTITUMORAL ACTIVITY | UNIVERSIDADE FEDERAL DE PERNAMBUCO - UFPE (BR) | 2007-10-04 | — | — | WO | disclosed |