⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1396809 | 0.89 | IDO1 (0.30) | — | |
| SCHEMBL4660459 | 0.86 | — | — | |
| SCHEMBL22578964 | 0.83 | — | — | |
| SCHEMBL869451 | 0.81 | — | — | |
| SCHEMBL22592864 | 0.81 | DGKA (0.33) | — | |
| SCHEMBL22578999 | 0.80 | NAAA (0.31) | — | |
| SCHEMBL22578918 | 0.79 | — | — | |
| SCHEMBL1396802 | 0.79 | IDO1 (0.33) | — | |
| SCHEMBL2700537 | 0.78 | SHBG (0.44) | — | |
| SCHEMBL13485527 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8569383-B2 | Utilization of rhinologically active substances | SYMRISE AG (DE) | 2013-10-29 | — | — | US | claimed |
| EP-1341512-B1 | RHINOLOGICAL AGENTS | SYMRISE GMBH & CO KG (DE) | 2008-12-31 | — | — | EP | claimed |
| US-7414079-B2 | Utilization of rhinologically active substances | SYMRISE GMBH & CO. KG (DE) | 2008-08-19 | — | — | US | claimed |
| US-20050027017-A1 | Rhinologically active substances | SYMRISE AG (DE) | 2005-02-03 | — | — | US | claimed |
| EP-1341512-A1 | RHINOLOGICAL AGENTS | HAARMANN & REIMER GMBH (DE) | 2003-09-10 | — | — | EP | claimed |
| US-20020120014-A1 | Rhinologically active substances | HAARMANN & REIMER GMBH (DE) | 2002-08-29 | — | — | US | claimed |
| WO-2002041861-A1 | RHINOLOGICAL AGENTS | HAARMANN & REIMER GMBH (DE) | 2002-05-30 | — | — | WO | claimed |
| US-8569383-B2 | Utilization of rhinologically active substances | SYMRISE AG (DE) | 2013-10-29 | — | — | US | disclosed |
| EP-1341512-B1 | RHINOLOGICAL AGENTS | SYMRISE GMBH & CO KG (DE) | 2008-12-31 | — | — | EP | disclosed |
| US-20080274064-A1 | UTILIZATION OF RHINOLOGICALLY ACTIVE SUBSTANCES | SYMRISE GMBH & CO. KG (DE) | 2008-11-06 | — | — | US | disclosed |
| US-7414079-B2 | Utilization of rhinologically active substances | SYMRISE GMBH & CO. KG (DE) | 2008-08-19 | — | — | US | disclosed |
| US-20050027017-A1 | Rhinologically active substances | SYMRISE AG (DE) | 2005-02-03 | — | — | US | disclosed |
| US-20020120014-A1 | Rhinologically active substances | HAARMANN & REIMER GMBH (DE) | 2002-08-29 | — | — | US | disclosed |