Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAAT3 | P53816 | 3/20 | 0.45 |
| ▸ | PLAAT5 | Q96KN8 | 3/20 | 0.45 |
| ▸ | PLAAT2 | Q9NWW9 | 3/20 | 0.45 |
| ▸ | PLAAT4 | Q9UL19 | 3/20 | 0.45 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.44 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.42 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.41 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.40 |
| ▸ | HTR3B | O95264 | 1/20 | 0.40 |
| ▸ | HTR3A | P46098 | 1/20 | 0.40 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.40 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.40 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4659398 | 1.00 | PLAAT3 (0.45) | PLAAT3PLAAT5PLAAT2PLAAT4TAAR1 | |
| SCHEMBL4660520 | 0.84 | CYP1A2 (0.43) | PLAAT3PLAAT5PLAAT2PLAAT4TAAR1 | |
| SCHEMBL4660802 | 0.84 | CYP1A2 (0.43) | PLAAT3PLAAT5PLAAT2PLAAT4TAAR1 | |
| SCHEMBL20845698 | 0.82 | ALDH1A1 (0.55) | FFAR1HDAC1HDAC6HDAC3HDAC4 | |
| SCHEMBL20845697 | 0.82 | ALDH1A1 (0.55) | FFAR1HDAC1HDAC6HDAC3HDAC4 | |
| SCHEMBL22375194 | 0.82 | ALDH1A1 (0.55) | FFAR1HDAC1HDAC6HDAC3HDAC4 | |
| SCHEMBL20708183 | 0.79 | AOC3 (0.42) | PLAAT3PLAAT5PLAAT2PLAAT4TAAR1 | |
| SCHEMBL7946947 | 0.79 | TAAR1 (0.50) | PLAAT3PLAAT5PLAAT2PLAAT4TAAR1 | |
| SCHEMBL1776 | 0.75 | ALDH1A1 (0.63) | PLAAT3PLAAT5PLAAT2PLAAT4TAAR1 | |
| SCHEMBL26784352 | 0.75 | IDO1 (0.48) | PLAAT3PLAAT5PLAAT2PLAAT4TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2004166-A2 | INHIBITORS OF SEMICARBAZIDE-SENSITIVE AMINE OXIDASE (SSAO) AND VAP-1 MEDIATED ADHESION USEFUL FOR TREATMENT AND PREVENTION OF DISEASES | LA JOLLA PHARMACEUTICAL COMPANY (US) | 2008-12-24 | — | — | EP | disclosed |
| WO-2007120528-A2 | INHIBITORS OF SEMICARBAZIDE-SENSITIVE AMINE OXIDASE (SSAO) AND VAP-1 MEDIATED ADHESION USEFUL FOR TREATMENT AND PREVENTION OF DISEASES | LA JOLLA PHARMACEUTICAL COMPANY (US) | 2007-10-25 | — | — | WO | disclosed |