Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 known ✓ | P08172 | 2/20 | 0.32 |
| ▸ | CHRM1 known ✓ | P11229 | 2/20 | 0.32 |
| ▸ | CHRM3 known ✓ | P20309 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 4/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.32 |
| ▸ | APEX1 | P27695 | 2/20 | 0.32 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 3/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 2/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3103825 | 0.99 | TSHR (0.39) | TSHRHTTKMT2ALMNAALDH1A1 | |
| SCHEMBL898823 | 0.83 | TSHR (0.39) | TSHRHTTKMT2ALMNAALDH1A1 | |
| SCHEMBL4372909 | 0.74 | TSHR (0.51) | TSHRHTTKMT2ALMNAALDH1A1 | |
| Ethylene SCHEMBL28313751 | 0.73 | TSHR (0.50) | TSHRHTTKMT2ALMNAALDH1A1 | |
| Hydrochloric Acid SCHEMBL868011 | 0.72 | TSHR (0.41) | TSHRHTTKMT2ALMNAALDH1A1 | |
| Hydrochloric Acid SCHEMBL5315766 | 0.70 | KMT2A (0.42) | TSHRHTTKMT2AALDH1A1RAB9A | |
| SCHEMBL28167209 | 0.68 | TSHR (0.50) | TSHRHTTKMT2ALMNAALDH1A1 | |
| Hydrochloric Acid SCHEMBL4412801 | 0.67 | TSHR (0.39) | TSHRHTTKMT2ALMNAALDH1A1 | |
| SCHEMBL8848376 | 0.67 | GAA (0.43) | TSHRHTTKMT2ALMNARAB9A | |
| SCHEMBL11760214 | 0.66 | TSHR (0.59) | TSHRHTTKMT2ALMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 198 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112638352-B | Composition comprising benefit agent-containing delivery particles | 恩盖普有限公司 | 2024-05-07 | — | — | CN | claimed |
| CN-116490068-A | Biodegradable delivery particles | 恩盖普有限公司 | 2023-07-25 | — | — | CN | claimed |
| CN-116323888-A | Consumer product comprising delivery particles with high core to wall ratio | 宝洁公司 | 2023-06-23 | — | — | CN | claimed |
| CN-116033963-A | Benefit agent-containing delivery particles with high core-to-wall ratio | 恩盖普有限公司 | 2023-04-28 | — | — | CN | claimed |
| EP-1531783-B1 | DETERGENT COMPOSITIONS | KAO CORP (JP) | 2010-11-17 | — | — | EP | claimed |
| EP-2178662-A1 | PRODUCTION OF METAL NANOPARTICLES | Cabot Corporation (US) | 2010-04-28 | — | — | EP | claimed |
| WO-2008151066-A1 | PRODUCTION OF METAL NANOPARTICLES | CABOT CORPORATION (US) | 2008-12-11 | — | — | WO | claimed |
| US-7244697-B2 | Detergent composition comprising a silicon derivative having a group containing both a hydroxy group and a nitrogen atom | KAO CORPORATION (JP) | 2007-07-17 | — | — | US | claimed |
| US-20060052273-A1 | Detergent compositions | KAO CORPORATION (JP) | 2006-03-09 | — | — | US | claimed |
| EP-1531783-A1 | DETERGENT COMPOSITIONS | Kao Corporation (JP) | 2005-05-25 | — | — | EP | claimed |
| WO-2004014326-A1 | DETERGENT COMPOSITIONS | KAO CORPORATION (JP) | 2004-02-19 | — | — | WO | claimed |
| WO-2024113195-A1 | A SOLID PARTICLE OF ORGANOSILICON-FUNCTIONAL CO-POLYMER, MANUFACTURING PROCESSTHEREOF, AND COSMETICS COMPRISING SAID SOLID PARTICLE | DOW TORAY CO., LTD. (JP) | 2024-06-06 | — | — | WO | disclosed |
| CN-112770713-B | Incorporation of chitosan into microcapsule walls | 恩盖普有限公司 | 2024-05-28 | — | — | CN | disclosed |
| CN-112638352-B | Composition comprising benefit agent-containing delivery particles | 恩盖普有限公司 | 2024-05-07 | — | — | CN | disclosed |
| CN-114672375-B | Composition comprising benefit agent-containing delivery particles | 宝洁公司 | 2024-04-19 | — | — | CN | disclosed |
| US-20030185783-A1 | Hair cleansing compositions | KAO CORPORATION (JP) | 2003-10-02 | — | — | US | disclosed |
| EP-1340488-A1 | Hair cleansing compositions comprising a hydroxymonocarboxylic acid | Kao Corporation (JP) | 2003-09-03 | — | — | EP | disclosed |
| EP-1306225-A2 | Multilayered inkjet recording element comprising pigments | EMTEC Magnetics GmbH (DE) | 2003-05-02 | — | — | EP | disclosed |
| US-20020193266-A1 | Detergent composition | KAO CORPORATION (JP) | 2002-12-19 | — | — | US | disclosed |
| WO-1997045510-A1 | FOAMING ACIDIC DETERGENT/CLEANSING GEL | SALIENT SCIENCE, INC. (US) | 1997-12-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030185783-A1 | Hair cleansing compositions | SHH, CUTA, POLR1C | CHRM2 4229/4885CHRM1 4591/4885CHRM3 4286/4885 |
| US-20020193266-A1 | Detergent composition | DEGS1, DAGLA, CUTA | CHRM2 1759/4885CHRM1 1555/4885CHRM3 2242/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.