Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.60 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | DRD1 | P21728 | 1/20 | 0.52 |
| ▸ | DRD4 | P21917 | 1/20 | 0.52 |
| ▸ | DRD5 | P21918 | 1/20 | 0.52 |
| ▸ | SYK | P43405 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | MITF | O75030 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | DRD2 | P14416 | 1/20 | 0.49 |
| ▸ | DRD3 | P35462 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5319656 | 0.91 | KDM4E (0.70) | KDM4ETDP1CYP2D6TSHRDRD1 | |
| Ammonia Solution, Strong SCHEMBL4267670 | 0.90 | KDM4E (0.68) | KDM4ETDP1CYP2D6TSHRDRD1 | |
| SCHEMBL12661473 | 0.80 | POLB (0.73) | TDP1CYP2D6TSHRDRD1DRD4 | |
| SCHEMBL14578233 | 0.78 | DRD1 (0.65) | KDM4ETDP1CYP2D6TSHRDRD1 | |
| SCHEMBL13744516 | 0.78 | SMN1; SMN2 (0.66) | KDM4ETDP1CYP2D6TSHRDRD1 | |
| SCHEMBL9200753 | 0.76 | TDP1 (0.50) | KDM4ETDP1CYP2D6TSHRALDH1A1 | |
| SCHEMBL3436048 | 0.76 | POLB (0.55) | KDM4ETDP1ALDH1A1POLBMITF | |
| SCHEMBL12058633 | 0.76 | TDP1 (0.74) | KDM4ETDP1CYP2D6DRD1DRD4 | |
| SCHEMBL9195296 | 0.75 | DRD2 (0.56) | KDM4ETDP1TSHRALDH1A1POLB | |
| SCHEMBL9200779 | 0.75 | ADRA1A (0.57) | KDM4ETDP1POLBMITFSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1741700-B1 | Process for the preparation of carvedilol | IPCA LAB LTD (IN) | 2008-12-24 | — | — | EP | disclosed |
| EP-1741700-A1 | Process for the preparation of carvedilol | IPCA Laboratories Limited (IN) | 2007-01-10 | — | — | EP | disclosed |