Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 10/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 9/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 7/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | ACACB | O00763 | 3/20 | 0.41 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.41 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.41 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.41 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.41 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13508844 | 0.80 | ACACB (0.47) | OPRM1OPRD1OPRK1ACACBGRIN2D | |
| SCHEMBL4661336 | 0.77 | ACACB (0.43) | OPRM1OPRD1OPRK1KDM4EGAA | |
| SCHEMBL3159306 | 0.75 | HSD17B10 (0.52) | KDM4EGAAMAPTL3MBTL1ABCB1 | |
| SCHEMBL4661367 | 0.74 | ACACB (0.42) | OPRM1OPRD1OPRK1ACACBMPO | |
| SCHEMBL510046 | 0.74 | LTA4H (0.58) | OPRM1OPRD1OPRK1ACACBGRIN2D | |
| SCHEMBL4661230 | 0.70 | MEN1 (0.44) | KDM4EMAPTL3MBTL1ABCB1ABCG2 | |
| SCHEMBL1845851 | 0.69 | FFAR1 (0.47) | OPRM1OPRD1KDM4EGAAMAPT | |
| SCHEMBL10483917 | 0.69 | OPRM1 (0.55) | OPRM1OPRD1OPRK1ACACBGRIN2D | |
| SCHEMBL28804944 | 0.68 | ACACB (0.44) | OPRM1OPRD1OPRK1ACACBGRIN2D | |
| SCHEMBL15177164 | 0.68 | ACACB (0.47) | OPRM1OPRD1OPRK1ACACBGRIN2D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2007707-A1 | COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | Boehringer Ingelheim International GmbH (DE) | 2008-12-31 | — | — | EP | disclosed |
| WO-2007118041-A1 | COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2007-10-18 | — | — | WO | disclosed |