Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 6/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 5/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 5/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.41 |
| ▸ | CTSA | P10619 | 2/20 | 0.41 |
| ▸ | GRN | P28799 | 2/20 | 0.41 |
| ▸ | SORT1 | Q99523 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ACACA | Q13085 | 2/20 | 0.41 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.40 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4661344 | 0.77 | OPRM1 (0.42) | ACACBOPRM1OPRD1OPRK1MAPT | |
| SCHEMBL10490374 | 0.76 | HSD17B10 (0.50) | MAPTKDM4EL3MBTL1 | |
| SCHEMBL1845851 | 0.76 | FFAR1 (0.47) | ACACBOPRM1OPRD1MAPTKDM4E | |
| SCHEMBL4661365 | 0.75 | ACACB (0.43) | ACACBOPRM1OPRD1OPRK1CTSA | |
| SCHEMBL2457278 | 0.73 | CASR (0.46) | ACACBOPRM1OPRD1OPRK1CTSA | |
| SCHEMBL3348544 | 0.73 | CASR (0.46) | ACACBOPRM1OPRD1OPRK1CTSA | |
| SCHEMBL12775823 | 0.72 | ACACB (0.50) | ACACBOPRM1OPRD1OPRK1GRN | |
| SCHEMBL4342037 | 0.72 | LMNA (0.53) | OPRM1OPRD1OPRK1KDM4EL3MBTL1 | |
| SCHEMBL4661227 | 0.71 | MEN1 (0.42) | MAPTKDM4EGAAL3MBTL1 | |
| SCHEMBL510046 | 0.70 | LTA4H (0.58) | ACACBOPRM1OPRD1OPRK1GRN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2007707-A1 | COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | Boehringer Ingelheim International GmbH (DE) | 2008-12-31 | — | — | EP | disclosed |
| WO-2007118041-A1 | COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2007-10-18 | — | — | WO | disclosed |