Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 3/20 | 0.43 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.33 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.33 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.33 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.33 |
| ▸ | KIF11 | P52732 | 4/20 | 0.33 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14938033 | 0.74 | ALDH1A1 (0.43) | MAPTALDH1A1MEN1GAAKMT2A | |
| SCHEMBL7025018 | 0.73 | TSHR (0.36) | ALDH1A1 | |
| SCHEMBL14843056 | 0.73 | ELANE (0.35) | KCNH2ELANEMAPTALDH1A1KIF11 | |
| SCHEMBL10062523 | 0.73 | ELANE (0.42) | KCNH2ELANEHTT | |
| Hydrochloric Acid SCHEMBL3899766 | 0.72 | MAPT (0.37) | KCNH2ELANEMAPTALDH1A1KDM4E | |
| SCHEMBL584058 | 0.72 | ALDH1A1 (0.38) | ALDH1A1 | |
| SCHEMBL47310 | 0.72 | ALDH1A1 (0.44) | ALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL23494164 | 0.72 | TSHR (0.37) | KCNH2ALDH1A1 | |
| SCHEMBL20924713 | 0.71 | ALDH1A1 (0.41) | ALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL2231481 | 0.71 | KCNH2 (0.36) | KCNH2ELANEMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1444239-B1 | HIGH REFRACTIVE INDEX AROMATIC-BASED SILYL MONOMERS | BAUSCH & LOMB (US) | 2008-12-24 | — | — | EP | disclosed |
| US-7132494-B2 | High refractive index aromatic-based silyl monomers | BAUSCH & LOMB INCORPORATED (US) | 2006-11-07 | — | — | US | disclosed |
| US-6881809-B2 | High refractive index aromatic-based silyl monomers | BAUSCH & LOMB INCORPORATED (US) | 2005-04-19 | — | — | US | disclosed |
| US-6846897-B2 | High refractive index aromatic-based silyl monomers | BAUSCH AND LOMB, INC. (US) | 2005-01-25 | — | — | US | disclosed |
| US-20040230023-A1 | High refractive index aromatic-based silyl monomers | SALAMONE JOSEPH C (US) | 2004-11-18 | — | — | US | disclosed |
| US-20040215156-A1 | High refractive index aromatic-based silyl monomers | SOLTA MEDICAL, INC. | 2004-10-28 | — | — | US | disclosed |
| US-20040215032-A1 | High refractive index aromatic-based silyl monomers | SALAMONE JOSEPH C | 2004-10-28 | — | — | US | disclosed |
| US-20040210023-A1 | High refractive index aromatic-based silyl monomers | SALAMONE JOSEPH C (US) | 2004-10-21 | — | — | US | disclosed |
| EP-1444239-A1 | HIGH REFRACTIVE INDEX AROMATIC-BASED SILYL MONOMERS | BAUSCH & LOMB INCORPORATED (US) | 2004-08-11 | — | — | EP | disclosed |
| US-6762271-B2 | INTRAOCULAR LENSES, CONTACT LENSES AND CORNEAL INLAYS | BAUSCH & LOMB INCORPORATED | 2004-07-13 | — | — | US | disclosed |
| US-20030105255-A1 | High refractive index aromatic-based silyl monomers | BAUSCH HEALTH, CANADA INC. / SANTE BAUSCH, CANADA INC. (CA) | 2003-06-05 | — | — | US | disclosed |
| WO-2003040152-A1 | HIGH REFRACTIVE INDEX AROMATIC-BASED SILYL MONOMERS | BAUSCH & LOMB INCORPORATED (US) | 2003-05-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040215032-A1 | High refractive index aromatic-based silyl monomers | SMAD2, SMAD3, FHIT | KCNH2 2237/4885ELANE 4250/4885MAPT 1090/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.