SCHEMBL47310

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL12184225	0.89	MAOB (0.43)	KMT2AMEN1PTPN1PTPRCMAOB
	SCHEMBL13559131	0.87	ALDH1A1 (0.53)	ALDH1A1KMT2AMEN1PTPN1PTPRC
	SCHEMBL10062523	0.84	ELANE (0.42)	CTRB1L3MBTL1TDP1
	SCHEMBL20924713	0.81	ALDH1A1 (0.41)	ALDH1A1KMT2ACTRB1TDP1SMN1; SMN2
	SCHEMBL20924759	0.81	ALDH1A1 (0.43)	ALDH1A1KMT2AMEN1PTPN1PTPRC
	SCHEMBL47314	0.81	THRB (0.38)	ALDH1A1TSHRLMNA
	SCHEMBL22662346	0.81	TSHR (0.30)	TSHR
	SCHEMBL12186473	0.79	HTT (0.36)	TSHR
	SCHEMBL1143936	0.78	TSHR (0.33)	ALDH1A1TSHR
	SCHEMBL12439401	0.78	TSHR (0.33)	TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.