Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.68 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 6/20 | 0.50 |
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.50 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4661745 | 1.00 | MEN1 (0.68) | MEN1KMT2ANR1H4MAPTLMNA | |
| SCHEMBL7300691 | 0.90 | MEN1 (0.68) | MEN1KMT2ANR1H4MAPTLMNA | |
| SCHEMBL7300688 | 0.90 | MEN1 (0.68) | MEN1KMT2ANR1H4MAPTLMNA | |
| SCHEMBL14198607 | 0.87 | MEN1 (0.72) | MEN1KMT2ANR1H4MAPTLMNA | |
| SCHEMBL13103426 | 0.87 | MEN1 (0.72) | MEN1KMT2ANR1H4MAPTLMNA | |
| Malonic Acid Diethyl Ester SCHEMBL8368278 | 0.85 | MEN1 (0.87) | MEN1KMT2ANR1H4MAPTLMNA | |
| SCHEMBL3331849 | 0.85 | KMT2A (0.49) | MEN1KMT2AMAPTLMNANPSR1 | |
| SCHEMBL5963732 | 0.84 | MEN1 (0.68) | MEN1KMT2ANR1H4MAPTLMNA | |
| SCHEMBL5963731 | 0.84 | MEN1 (0.68) | MEN1KMT2ANR1H4MAPTLMNA | |
| SCHEMBL18961296 | 0.83 | KMT2A (0.50) | MEN1KMT2AMAPTLMNANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1392638-B1 | PROCESS FOR PREPARING ALKYLIDENE SUBSTITUTED SUCCINIC ACID ESTERS | BASELL POLIOLEFINE ITALIA SRL (IT) | 2016-12-14 | — | — | EP | disclosed |
| EP-1527039-B1 | PROCESS FOR PREPARING ALKYLIDENE-SUBSTITUTED-1,4-DIONS DERIVATIVES | BASELL POLIOLEFINE SRL (IT) | 2008-12-24 | — | — | EP | disclosed |
| US-7465821-B2 | Process for preparing alkylidene-substituted-1, 4-dions derivatives | BASELL POLIOLEFINE ITALIA S.P.A. (IT) | 2008-12-16 | — | — | US | disclosed |
| US-7399879-B2 | Process for preparing alkylidene-substituted-1,4-dions derivatives | BASELL POLIOLEFINE ITALIA S.P.A. (IT) | 2008-07-15 | — | — | US | disclosed |
| US-6914153-B2 | Process for preparing alkylidene substituted succinic acid esters | BASSELL POLIOLEFINE ITALIA S.P.A. (IT) | 2005-07-05 | — | — | US | disclosed |
| US-20050113599-A1 | Process for preparing alkylidene-substituted -1, 4-dions derivatives | BASELL POLIOLEFINE ITALIA S.P.A. (IT) | 2005-05-26 | — | — | US | disclosed |
| EP-1527039-A1 | PROCESS FOR PREPARING ALKYLIDENE-SUBSTITUTED-1,4-DIONS DERIVATIVES | Basell Poliolefine Italia S.P.A. (IT) | 2005-05-04 | — | — | EP | disclosed |
| EP-1527040-A1 | PROCESS FOR PREPARING ALKYLIDENE-SUBSTITUTED-1,4-DIONS DERIVATIVES | Basel Poliolefine Italia SpA (IT) | 2005-05-04 | — | — | EP | disclosed |
| US-20050080290-A1 | Process for preparing alkylidene-substituted-1, 4-dions derivatives | BASELL POLIOLEFINE ITALIA S.P.A. (IT) | 2005-04-14 | — | — | US | disclosed |
| EP-1392638-A1 | PROCESS FOR PREPARING ALKYLIDENE SUBSTITUTED SUCCINIC ACID ESTERS | Basell Poliolefine Italia S.p.A. (IT) | 2004-03-03 | — | — | EP | disclosed |
| WO-2004014838-A1 | PROCESS FOR PREPARING ALKYLIDENE-SUBSTITUTED-1,4-DIONS DERIVATIVES | BASELL POLIOLEFINE ITALIA S.P.A. (IT) | 2004-02-19 | — | — | WO | disclosed |
| WO-2004014839-A1 | PROCESS FOR PREPARING ALKYLIDENE-SUBSTITUTED-1,4-DIONS DERIVATIVES | BASEL POLIOLEFINE ITALIA S.P.A. (IT) | 2004-02-19 | — | — | WO | disclosed |
| US-20030181743-A1 | Process for preparing alkylidene substituted succinic acid esters | BASELL POLIOLEFINE ITALIA S.P.A. (IT) | 2003-09-25 | — | — | US | disclosed |
| WO-2002098837-A1 | PROCESS FOR PREPARING ALKYLIDENE SUBSTITUTED SUCCINIC ACID ESTERS | BASELL POLIOLEFINE ITALIA S.P.A (IT) | 2002-12-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050113599-A1 | Process for preparing alkylidene-substituted -1, 4-dions derivatives | KCNJ4, NR3C2, NR4A2 | MEN1 793/4885KMT2A 626/4885NR1H4 49/4885 |
| US-20030181743-A1 | Process for preparing alkylidene substituted succinic acid esters | OGDH, SCO2, SUCNR1 | MEN1 1685/4885KMT2A 980/4885NR1H4 1466/4885 |
| US-20050080290-A1 | Process for preparing alkylidene-substituted-1, 4-dions derivatives | RTN4, NR4A2, NR3C2 | MEN1 1855/4885KMT2A 2796/4885NR1H4 30/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.