SCHEMBL46621

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL19168035	0.82	GPX4 (0.39)	TRPV1MEN1KMT2AGPX4MAPT
	SCHEMBL24690641	0.82	MCHR1 (0.40)	MEN1KMT2AMAPK1MAPTPRMT5
	SCHEMBL30022326	0.82	MCHR1 (0.40)	MEN1KMT2AMAPK1MAPTPRMT5
	SCHEMBL19167946	0.80	GPX4 (0.42)	TRPV1MEN1KMT2AMAPK1GPX4
	SCHEMBL19168827	0.80	GPX4 (0.42)	TRPV1MEN1KMT2AFAAHGPX4
	SCHEMBL21154454	0.79	LMNA (0.55)	TRPV1MEN1KMT2AFAAHGPX4
	SCHEMBL24447655	0.78	CYP19A1 (0.45)	TRPV1MEN1KMT2AMAPTKDM4E
	SCHEMBL19168872	0.77	MAPT (0.42)	TRPV1MEN1KMT2AFAAHGPX4
	SCHEMBL350201	0.76	TRPV1 (0.69)	TRPV1FAAHGPX4LMNAMAPT
	SCHEMBL19167692	0.76	MAPT (0.41)	MEN1KMT2AGPX4LMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.