Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20835283 | 0.92 | OPRM1 (0.36) | TSHRKDM4ESMN1; SMN2MAPTALOX15 | |
| SCHEMBL11494978 | 0.92 | KDM4E (0.34) | TSHRKDM4ESMN1; SMN2MAPTALOX15 | |
| SCHEMBL147493 | 0.92 | TSHR (0.37) | TSHRKDM4ESMN1; SMN2MAPTALOX15 | |
| SCHEMBL170617 | 0.92 | OPRM1 (0.38) | TSHRKDM4ESMN1; SMN2MAPTALOX15 | |
| Ammonia Solution, Strong SCHEMBL4662387 | 0.89 | OPRM1 (0.37) | TSHRKDM4ESMN1; SMN2MAPTALOX15 | |
| Hydrochloric Acid SCHEMBL1234433 | 0.89 | OPRM1 (0.40) | TSHRKDM4ESMN1; SMN2MAPTALOX15 | |
| Bromide SCHEMBL11042426 | 0.89 | KDM4E (0.35) | TSHRKDM4ESMN1; SMN2MAPTALOX15 | |
| Hydrochloric Acid SCHEMBL7722967 | 0.89 | OPRK1 (0.36) | TSHRKDM4ESMN1; SMN2MAPTALOX15 | |
| SCHEMBL31711370 | 0.89 | OPRM1 (0.37) | TSHRKDM4ESMN1; SMN2MAPTALOX15 | |
| SCHEMBL11493587 | 0.87 | KDM4E (0.33) | TSHRKDM4ESMN1; SMN2OPRM1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0239062-B1 | N2-(1-CARBOXY-3-OXO-3-PHENYLPROPYL)-L-LYSINE COMPOUNDS AND THEIR DERIVATIVES | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1991-05-29 | — | — | EP | disclosed |
| EP-0239062-A2 | N2-(1-carboxy-3-oxo-3-phenylpropyl)-L-Lysine compounds and their derivatives | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1987-09-30 | — | — | EP | disclosed |