Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMS | P04818 | 2/20 | 0.46 |
| ▸ | MMP2 | P08253 | 2/20 | 0.43 |
| ▸ | MMP9 | P14780 | 2/20 | 0.43 |
| ▸ | MMP8 | P22894 | 2/20 | 0.43 |
| ▸ | MMP13 | P45452 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | HTR6 | P50406 | 2/20 | 0.41 |
| ▸ | HTR2A | P28223 | 2/20 | 0.40 |
| ▸ | HTR2C | P28335 | 2/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.40 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4661305 | 0.80 | PYCR1 (0.42) | TSHRHTTL3MBTL1ALDH1A1MAPT | |
| SCHEMBL4661399 | 0.80 | PYCR1 (0.42) | TSHRHTTL3MBTL1ALDH1A1MAPT | |
| SCHEMBL4661323 | 0.80 | ALDH1A1 (0.41) | MMP2MMP9MMP8MMP13TSHR | |
| SCHEMBL4661500 | 0.80 | ALDH1A1 (0.41) | MMP2MMP9MMP8MMP13TSHR | |
| SCHEMBL4664193 | 0.76 | TYMS (0.46) | TYMSHTR6HTR2AHTR2CNR1H3 | |
| SCHEMBL12083406 | 0.74 | ALDH1A1 (0.59) | TYMSTSHRHTTHTR6HTR2A | |
| SCHEMBL4346578 | 0.74 | KDM4E (0.64) | TYMSHTR6L3MBTL1ALDH1A1SMN1; SMN2 | |
| SCHEMBL4662697 | 0.73 | NAMPT (0.42) | HTR6HTR2AHTR2CKCNH2L3MBTL1 | |
| SCHEMBL4661432 | 0.73 | NAMPT (0.42) | HTR6HTR2AHTR2CKCNH2L3MBTL1 | |
| SCHEMBL4662728 | 0.72 | MMP2 (0.43) | MMP2MMP9MMP8MMP13KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2007707-A1 | COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | Boehringer Ingelheim International GmbH (DE) | 2008-12-31 | — | — | EP | claimed |
| WO-2007118041-A1 | COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2007-10-18 | — | — | WO | claimed |
| EP-2007707-A1 | COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | Boehringer Ingelheim International GmbH (DE) | 2008-12-31 | — | — | EP | disclosed |
| WO-2007118041-A1 | COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2007-10-18 | — | — | WO | disclosed |