Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CMA1 | P23946 | 3/20 | 0.39 |
| ▸ | CTSG | P08311 | 1/20 | 0.39 |
| ▸ | ACP3 | P15309 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.38 |
| ▸ | MGAM | O43451 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 3/20 | 0.36 |
| ▸ | SI | P14410 | 3/20 | 0.36 |
| ▸ | MGAM2 | Q2M2H8 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.35 |
| ▸ | UGT2B7 | P16662 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.34 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4660186 | 0.87 | PPARG (0.37) | ACP3PPARGPPARAMGAMGAA | |
| SCHEMBL4660128 | 0.87 | ACP3 (0.42) | ACP3PPARGPPARAALDH1A1CYP2C9 | |
| SCHEMBL4661453 | 0.87 | MEN1 (0.45) | PPARGPPARACYP2C9CYP2C19MTNR1A | |
| SCHEMBL4661436 | 0.85 | MEN1 (0.36) | PPARGPPARAALDH1A1CYP2C9HPGD | |
| SCHEMBL4661396 | 0.85 | PPARG (0.38) | ACP3PPARGPPARAGAAALDH1A1 | |
| SCHEMBL4662672 | 0.84 | MAPT (0.43) | PPARGPPARAGAAALDH1A1HPGD | |
| SCHEMBL4662654 | 0.82 | PPARG (0.38) | ACP3PPARGPPARAALDH1A1CYP2C9 | |
| SCHEMBL4661407 | 0.81 | PPARG (0.46) | ACP3PPARGPPARACYP2C9HPGD | |
| SCHEMBL4661587 | 0.81 | ESR1 (0.45) | PPARGPPARAGAAALDH1A1HPGD | |
| SCHEMBL4662804 | 0.80 | ALDH1A1 (0.45) | PPARGPPARAALDH1A1HPGDMTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1620102-B1 | 3-(1-NAPHTHYL)-2-CYANOPROPANOIC ACID DERIVATIVES AS ESTROGEN RECEPTOR LIGANDS | WYETH CORP (US) | 2008-12-24 | — | — | EP | claimed |