Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | GCK | P35557 | 3/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 2/20 | 0.40 |
| ▸ | DHODH | Q02127 | 1/20 | 0.40 |
| ▸ | PTGES | O14684 | 1/20 | 0.40 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | CCR5 | P51681 | 1/20 | 0.39 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7619113 | 0.81 | L3MBTL1 (0.54) | STAT3HTTSMN1; SMN2BRD4L3MBTL1 | |
| SCHEMBL1942332 | 0.79 | DHODH (0.52) | STAT3HTTSMN1; SMN2GCKBRD4 | |
| SCHEMBL30501988 | 0.79 | DHODH (0.52) | STAT3HTTSMN1; SMN2GCKBRD4 | |
| SCHEMBL4715517 | 0.78 | LMNA (0.52) | STAT3HTTSMN1; SMN2L3MBTL1MAPT | |
| SCHEMBL16428100 | 0.73 | STAT3 (0.46) | STAT3HTTSMN1; SMN2GCKL3MBTL1 | |
| SCHEMBL5591575 | 0.71 | PPARA (0.47) | STAT3HTTSMN1; SMN2MAPTPTGER1 | |
| SCHEMBL9528492 | 0.70 | MAPT (0.54) | STAT3HTTSMN1; SMN2BRD4L3MBTL1 | |
| SCHEMBL8924430 | 0.70 | MAOB (0.53) | HTTSMN1; SMN2L3MBTL1MAPTMAPK1 | |
| SCHEMBL16926498 | 0.70 | GCK (0.55) | STAT3HTTSMN1; SMN2GCKBRD4 | |
| SCHEMBL24507623 | 0.69 | MAOB (0.47) | KDM1AMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080113963-A1 | Cyclic benzimidazoles | ALTANA PHARMA AG (DE) | 2008-05-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080113963-A1 | Cyclic benzimidazoles | VIP, GIPR, SI | STAT3 3505/4885HTT 3370/4885SMN1; SMN2 4603/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.