Sugi Predict

Sugi Predict / Compounds / Clazuril

Clazuril

Clazuril

SCHEMBL466311

N#CC(c1ccc(Cl)cc1)c1ccc(-n2ncc(=O)[nH]c2=O)cc1Cl

nearest known ligand 0.78

Full drug profile on Sugi Atlas →

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 1/20 0.78
▸ NR1I2 O75469 1/20 0.78
▸ KMT2A Q03164 1/20 0.78
▸ LMNA P02545 1/20 0.43
▸ POLB P06746 1/20 0.43
▸ P2RX7 Q99572 10/20 0.42
▸ THRB P10828 5/20 0.40
▸ THRA P10827 4/20 0.40
▸ ABCB11 O95342 1/20 0.39
▸ ALDH1A1 P00352 1/20 0.36
▸ GAA P10253 1/20 0.36
▸ L3MBTL1 Q9Y468 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10420028 0.92 KMT2A (0.66) MEN1NR1I2KMT2ALMNAPOLB
SCHEMBL10671723 0.92 MEN1 (0.66) MEN1NR1I2KMT2ALMNAPOLB
SCHEMBL9823418 0.91 KMT2A (0.67) MEN1NR1I2KMT2ALMNAPOLB
Diclazuril SCHEMBL126138 0.88 MEN1 (1.00) MEN1NR1I2KMT2AP2RX7THRB
SCHEMBL6493238 0.87 KMT2A (0.78) MEN1NR1I2KMT2ALMNAP2RX7
SCHEMBL5561279 0.84 KMT2A (0.60) MEN1NR1I2KMT2AP2RX7THRB
SCHEMBL5565971 0.83 KMT2A (0.59) MEN1NR1I2KMT2AP2RX7THRB
SCHEMBL10421658 0.83 MEN1 (0.59) MEN1NR1I2KMT2AP2RX7THRB
SCHEMBL5566912 0.83 KMT2A (0.59) MEN1NR1I2KMT2AP2RX7THRB
SCHEMBL7919703 0.83 MEN1 (0.86) MEN1NR1I2KMT2AP2RX7THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 356 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113624880-B High-throughput screening method for residual medicines in honey 深圳海关食品检验检疫技术中心 2023-08-04 — — CN claimed
US-11246836-B2 Intramuscular depot of decoquinate compositions and method of prophylaxis and treatment thereof BLUELIGHT PHARMATECH CO., LTD. (CN) 2022-02-15 — — US claimed
US-20210059946-A1 INTRAMUSCULAR DEPOT OF DECOQUINATE COMPOSITIONS AND METHOD OF PROPHYLAXIS AND TREATMENT THEREOF CAS LAMVAC (GUANGZHOU) BIOMEDICAL TECHNOLOGY CO., LTD. (CN) 2021-03-04 — — US claimed
CN-107255686-B Analysis method for determining multi-veterinary drug residues in aquaculture water 中山出入境检验检疫局检验检疫技术中心 2020-03-27 — — CN claimed
CN-110849990-A Method for detecting veterinary drug residues in animal-derived food and application thereof 中国肉类食品综合研究中心 2020-02-28 — — CN claimed
WO-2019218305-A1 INTRAMUSCULAR DEPOT OF DECOQUINATE COMPOSITIONS AND METHOD OF PROPHYLAXIS AND TREATMENT THEREOF Bluelight Pharmatech Co., Ltd (CN) 2019-11-21 — — WO claimed
CN-107167539-B Detection method for rapidly screening various veterinary drug residues in fish meat 中山出入境检验检疫局检验检疫技术中心 2019-07-23 — — CN claimed
CN-109496152-A The method of the intramuscular inventory and its prevention and treatment of deccox composition 广州蓝亮医药科技有限公司 2019-03-19 — — CN claimed
CN-107255686-A Analysis method for determining multi-veterinary drug residues in aquaculture water 中山出入境检验检疫局检验检疫技术中心 2017-10-17 — — CN claimed
US-20170291886-A1 METHODS FOR TREATING PROTOZOAN INFECTIONS NEOCULI PTY LTD (AU) 2017-10-12 — — US claimed
WO-2000019964-A2 NOVEL COMPOSITIONS AND METHODS FOR PREVENTION AND TREATMENT OF PROTOZOAL DISEASE NEW ACE RESEARCH COMPANY (US) 2000-04-13 — — WO claimed
US-5883095-A TRIAZINE ANTICOCCIDAL USING CLAZURIL, DICLAZURIL, TOLTRAZURIL OR LETRAZURIL UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) 1999-03-16 — — US claimed
US-5830893-A Treatment of equine protozoan myeloencephalitis using triazinediones MORTAR & PESTLE VETERINARY PHARMACY, INC. (US) 1998-11-03 — — US claimed
WO-1998043644-A1 FORMULATIONS AND METHODS TO TREAT AND PREVENT EQUINE PROTOZOAL MYELOENCEPHALITIS GRANSTROM DAVID (US) 1998-10-08 — — WO claimed
EP-0377904-B1 AGENT AGAINST PROTOZOAE IN INSECTS BAYER AG (DE) 1993-08-18 — — EP claimed
EP-0353526-B1 AGENT AGAINST FISH PARASITES CONTAINING TRIAZINEDIONE DERIVATIVES BAYER AG (DE) 1993-05-26 — — EP claimed
US-5070091-A HONEY BEES BAYER AKTIENGESELLSCHAFT (DE) 1991-12-03 — — US claimed
EP-0170316-B1 ALPHA-ARYL-4-(4,5-DIHYDRO-3,5-DIOXO-1,2,4-TRIAZIN-2(3H)-YL)BENZENEACETONITRILES JANSSEN PHARMACEUTICA N.V. (BE) 1990-05-30 — — EP claimed
US-4631278-A Anti-protozoal α-aryl-4-(4,5-dihydro-3,5-dioxo-1,2,4-triazin-2(3H)-yl)-benzeneacetonitrile derivatives, pharmaceutical compositions, and method of use therefor JANSSEN PHARMACEUTICA N.V. (BE) 1986-12-23 — — US claimed
EP-0170316-A2 alpha-Aryl-4-(4,5-dihydro-3,5-dioxo-1,2,4-triazin-2(3H)-yl)benzeneacetonitriles JANSSEN PHARMACEUTICA N.V. (BE) 1986-02-05 — — EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170291886-A1 METHODS FOR TREATING PROTOZOAN INFECTIONS DPM1, ABCB11, PIGS MEN1 504/4885NR1I2 1005/4885KMT2A 2912/4885
US-20210059946-A1 INTRAMUSCULAR DEPOT OF DECOQUINATE COMPOSITIONS AND METHOD OF PROPHYLAXIS AND TREATMENT THEREOF HMGCR, DECR1, GYS1 MEN1 1900/4885NR1I2 650/4885KMT2A 2101/4885
US-11246836-B2 Intramuscular depot of decoquinate compositions and method of prophylaxis and treatment thereof HMGCR, DECR1, GYS1 MEN1 1900/4885NR1I2 650/4885KMT2A 2101/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.