Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2R | P25116 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | ABL1 | P00519 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28044646 | 0.86 | RAPGEF4 (0.47) | F2RMAPTHTTABL1CYP1A2 | |
| SCHEMBL18631859 | 0.84 | HDAC4 (0.49) | F2RMAPTHTTABL1CYP1A2 | |
| SCHEMBL8667014 | 0.83 | F2R (0.56) | F2RMAPTHTTABL1CYP1A2 | |
| SCHEMBL5004348 | 0.83 | HTR7 (0.52) | F2RMAPTHTTABL1CYP1A2 | |
| SCHEMBL28848114 | 0.83 | F2R (0.45) | F2RMAPTHTTABL1CYP1A2 | |
| SCHEMBL27705880 | 0.80 | TLR8 (0.50) | F2RMAPTHTTABL1CYP1A2 | |
| SCHEMBL9827733 | 0.80 | F2R (0.43) | F2RMAPTHTTABL1CYP1A2 | |
| SCHEMBL15946031 | 0.79 | HDAC4 (0.48) | MAPTHTTABL1CYP1A2CYP3A4 | |
| SCHEMBL11522061 | 0.79 | EPHX1 (0.55) | F2RMAPTHTTABL1CYP1A2 | |
| SCHEMBL11410042 | 0.78 | S1PR1 (0.53) | ABL1HDAC11HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080122428-A1 | Optimized Determination of Voltage Changes Using a Voltage-Sensitive Dye | MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNGDER WISSENSCHAFTEN E. V. (DE) | 2008-05-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080122428-A1 | Optimized Determination of Voltage Changes Using a Voltage-Sensitive Dye | HVCN1, CACNG5, CACNB4 | F2R 4360/4885MAPT 2799/4885HTT 2901/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.