Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIT | P10721 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.36 |
| ▸ | CDK9 | P50750 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 5/20 | 0.36 |
| ▸ | TNNI3K | Q59H18 | 2/20 | 0.36 |
| ▸ | ABL1 | P00519 | 4/20 | 0.36 |
| ▸ | BCR | P11274 | 4/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.34 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.34 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Formic Acid SCHEMBL4665725 | 0.94 | KIT (0.41) | KITLMNACCNT1CDK9SCN9A | |
| Formic Acid SCHEMBL4666169 | 0.89 | HTR6 (0.46) | KITLMNACCNT1CDK9 | |
| Formic Acid SCHEMBL4667419 | 0.87 | HTR6 (0.48) | KITLMNACCNT1CDK9SCN9A | |
| SCHEMBL4663854 | 0.86 | USP2 (0.35) | KITLMNACCNT1CDK9TNNI3K | |
| Formic Acid SCHEMBL4663865 | 0.85 | HTR6 (0.43) | KITLMNACCNT1CDK9TNNI3K | |
| Formic Acid SCHEMBL4663848 | 0.85 | RORC (0.35) | KITABL1BCRBACE1TP53 | |
| Formic Acid SCHEMBL4667448 | 0.84 | LMNA (0.41) | KITLMNACCNT1CDK9SCN9A | |
| SCHEMBL4665730 | 0.80 | BACE1 (0.34) | KITLMNACCNT1CDK9SCN9A | |
| SCHEMBL4666185 | 0.80 | LMNA (0.43) | KITLMNACCNT1CDK9SCN9A | |
| Formic Acid SCHEMBL4664389 | 0.79 | RORC (0.34) | KITCCNT1CDK9ABL1BCR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080242681-A1 | N-4-(6-(Hetero)Aryl-Pyrimidin-4-Ylaminophenyl)-Benzenesulfonamides as Kinase Inhibitors | ALTANA PHARMA AG (DE) | 2008-10-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080242681-A1 | N-4-(6-(Hetero)Aryl-Pyrimidin-4-Ylaminophenyl)-Benzenesulfonamides as Kinase Inhibitors | MAP3K19, MAP3K6, MAP3K20 | KIT 675/4885LMNA 4261/4885CCNT1 217/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.