Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.35 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.35 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.35 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.35 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL510121 | 0.86 | SRC (0.48) | SRCALDH1A1AKR1C3AKR1C2TAS1R3 | |
| SCHEMBL2167808 | 0.82 | CYP1A2 (0.41) | SRCALDH1A1TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL3081525 | 0.81 | TAS1R3 (0.42) | SRCALDH1A1AKR1C3AKR1C2TAS1R3 | |
| SCHEMBL3001746 | 0.78 | SRC (0.40) | SRCALDH1A1TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL28732227 | 0.77 | SRC (0.38) | SRCALDH1A1AKR1C3AKR1C2TAS1R3 | |
| SCHEMBL509088 | 0.76 | AKR1C3 (0.41) | SRCALDH1A1AKR1C3AKR1C2MEN1 | |
| SCHEMBL2429894 | 0.75 | SRC (0.36) | SRCSLC6A2SMN1; SMN2MEN1KMT2A | |
| SCHEMBL509062 | 0.75 | SRC (0.47) | SRCALDH1A1LMNATRPA1CHRM1 | |
| SCHEMBL28693586 | 0.74 | SRC (0.41) | SRCALDH1A1TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL15326052 | 0.73 | ALDH1A1 (0.50) | ALDH1A1AKR1C3AKR1C2LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9096534-B2 | Pyridazinone compound and use thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2015-08-04 | — | — | US | disclosed |
| US-9096533-B2 | Pyridazinone compound and use thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2015-08-04 | — | — | US | disclosed |
| US-20150126738-A1 | PYRIDAZINONE COMPOUND AND USE THEREOF | SUMITOMO CHEMICAL CO (JP) | 2015-05-07 | — | — | US | disclosed |
| US-20150126739-A1 | PYRIDAZINONE COMPOUND AND USE THEREOF | SUMITOMO CHEMICAL CO (JP) | 2015-05-07 | — | — | US | disclosed |
| US-8962625-B2 | Pyridazinone compound and use thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2015-02-24 | — | — | US | disclosed |
| US-8541414-B2 | Pyridazinone compound and use thereof as herbicides | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2013-09-24 | — | — | US | disclosed |
| US-8507410-B2 | Pyridazinone compound and use thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2013-08-13 | — | — | US | disclosed |
| US-8435549-B2 | Halogen alkoxy spirocyclic tetramic and tetronic acid derivatives | BAYER CROPSCIENCE AG (DE) | 2013-05-07 | — | — | US | disclosed |
| US-8383853-B2 | Method for preparing 2,6-diethyl-4-methylphenylacetic acid | BAYER CROPSCIENCE AG (DE) | 2013-02-26 | — | — | US | disclosed |
| US-20120196750-A1 | PYRIDAZINONE COMPOUND AND USE THEREOF | KIJI TOSHIYUKI (JP) | 2012-08-02 | — | — | US | disclosed |
| EP-2187745-A2 | HERBICIDAL COMPOSITION | Sumitomo Chemical Company, Limited (JP) | 2010-05-26 | — | — | EP | disclosed |
| EP-2187744-A2 | HERBICIDAL COMPOSITION COMPRISING A PYRIDAZINONE COMPOUND WITH A SPECIFIC HERBICIDE AND A SPECIFIC SAFENER | Sumitomo Chemical Company, Limited (JP) | 2010-05-26 | — | — | EP | disclosed |
| EP-1996557-B1 | PYRIDAZINONE COMPOUND AND USE THEREOF AS HERBICIDES | SUMITOMO CHEMICAL CO (JP) | 2010-03-03 | — | — | EP | disclosed |
| US-20090111696-A1 | Pyridazinone Compound and Use Thereof as herbicides | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2009-04-30 | — | — | US | disclosed |
| WO-2009035145-A2 | HERBICIDAL COMPOSITION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2009-03-19 | — | — | WO | disclosed |
| WO-2009035151-A2 | HERBICIDAL COMPOSITION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2009-03-19 | — | — | WO | disclosed |
| WO-2009035146-A2 | HERBICIDAL COMPOSITION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2009-03-19 | — | — | WO | disclosed |
| US-20080318776-A1 | 2,6-Diethyl-4-Methylphenyl-Substituted Tetramic Acid Derivatives | BAYER CROPSCIENCE AG (DE) | 2008-12-25 | — | — | US | disclosed |
| EP-1996557-A1 | PYRIDAZINONE COMPOUND AND USE THEREOF AS HERBICIDES | Sumitomo Chemical Company, Limited (JP) | 2008-12-03 | — | — | EP | disclosed |
| WO-2007119434-A1 | PYRIDAZINONE COMPOUND AND USE THEREOF AS HERBICIDES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-10-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150126738-A1 | PYRIDAZINONE COMPOUND AND USE THEREOF | PDXK, PLPBP, PNPO | SRC 4792/4885ALDH1A1 331/4885AKR1C3 898/4885 |
| US-20150126739-A1 | PYRIDAZINONE COMPOUND AND USE THEREOF | PDXK, PLPBP, PNPO | SRC 4792/4885ALDH1A1 331/4885AKR1C3 898/4885 |
| US-20080318776-A1 | 2,6-Diethyl-4-Methylphenyl-Substituted Tetramic Acid Derivatives | DDT, TET1, TET3 | SRC 3276/4885ALDH1A1 992/4885AKR1C3 2811/4885 |
| US-20120196750-A1 | PYRIDAZINONE COMPOUND AND USE THEREOF | PDXK, PLPBP, PNPO | SRC 4792/4885ALDH1A1 331/4885AKR1C3 898/4885 |
| US-20090111696-A1 | Pyridazinone Compound and Use Thereof as herbicides | PDXK, DDT, PLPBP | SRC 4272/4885ALDH1A1 171/4885AKR1C3 742/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.