SCHEMBL4664314

SCHEMBL4664314

CCCCC([C]=O)=Cc1ccccc1

nearest known ligand 0.54

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.54
TDP1 Q9NUW8 1/20 0.53
CES2 O00748 2/20 0.43
CES1 P23141 2/20 0.43
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42
RECQL P46063 2/20 0.41
PTGS2 P35354 1/20 0.41
KDM4E B2RXH2 1/20 0.41
ALDH1A1 P00352 1/20 0.40
TSHR P16473 1/20 0.40
AKR1C3 P42330 1/20 0.40
NR1I2 O75469 1/20 0.40
ELANE P08246 1/20 0.39
EGFR P00533 1/20 0.39
HDAC3 O15379 1/20 0.39
MCL1 Q07820 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2534838 0.95 LMNA (0.61) LMNATDP1CES2CES1MEN1
SCHEMBL20143067 0.84 LMNA (0.49) LMNATDP1CES2CES1MEN1
SCHEMBL8553716 0.83 KDM1A (0.46) LMNATDP1MEN1KMT2ARECQL
SCHEMBL28752642 0.79 LMNA (0.55) LMNATDP1CES2CES1MEN1
SCHEMBL30481108 0.79 LMNA (0.55) LMNATDP1CES2CES1MEN1
SCHEMBL28752643 0.78 TDP1 (0.56) LMNATDP1CES2CES1ALDH1A1
SCHEMBL93497 0.77 LMNA (0.56) LMNATDP1CES2CES1MEN1
SCHEMBL7625514 0.77 MCL1 (0.43) LMNAMEN1KMT2ARECQLALDH1A1
SCHEMBL14690678 0.76 KEAP1 (0.48) LMNATDP1ALDH1A1HDAC3MCL1
SCHEMBL2802060 0.76 LMNA (0.51) LMNATDP1CES2CES1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115697281-B Shear thinning cosmetic composition ELC管理有限责任公司 2024-04-05 CN disclosed
CN-111163753-B Inorganic sun-screening agent with high ultraviolet radiation protection 维佐尔有限责任公司 2023-10-31 CN disclosed
EP-1830784-A4 ANTI-AGING METHODS AND COMPOSITION AQUAPHOTONICS INC (US) 2008-12-31 EP disclosed
EP-1830784-A1 ANTI-AGING METHODS AND COMPOSITION Aquaphotonics, Inc. (US) 2007-09-12 EP disclosed
WO-2006065920-A1 ANTI-AGING METHODS AND COMPOSITION AQUAPHOTONICS, INC. (US) 2006-06-22 WO disclosed
EP-1670435-A2 FOAM CARRIER CONTAINING AMPHIPHILIC COPOLYMERIC GELLING AGENT Foamix Ltd. (IL) 2006-06-21 EP disclosed
WO-2005011567-A2 FOAM CARRIER CONTAINING AMPHIPHILIC COPOLYMERIC GELLING AGENT FOAMIX LTD. (US) 2005-02-10 WO disclosed
EP-0896522-B1 METHODS OF REGULATING SKIN APPEARANCE WITH VITAMIN B 3 COMPOUND PROCTER & GAMBLE (US) 2003-10-22 EP disclosed
EP-1267802-A2 LEAVE-IN HAIR COSMETIC COMPOSITIONS FOR ENHANCING VOLUME CONTAINING MICROSPHERES THE PROCTER & GAMBLE COMPANY (US) 2003-01-02 EP disclosed
EP-1221852-A2 ANTIMICROBIAL COMPOSITIONS COMPRISING A BENZOIC ACID ANALOG AND A METAL SALT The Procter & Gamble Company (US) 2002-07-17 EP disclosed
EP-0909161-B1 SKIN LIGHTENING COMPOSITIONS PROCTER & GAMBLE (US) 2002-05-15 EP disclosed
WO-2001074310-A2 LEAVE-IN HAIR COSMETIC COMPOSITIONS FOR ENHANCING VOLUME CONTAINING MICROSPHERES THE PROCTER & GAMBLE COMPANY (US) 2001-10-11 WO disclosed
WO-2001028338-A2 ANTIMICROBIAL COMPOSITIONS COMPRISING A BENZOIC ACID ANALOG AND A METAL SALT THE PROCTER & GAMBLE COMPANY (US) 2001-04-26 WO disclosed
EP-0983053-A1 SKIN CARE COMPOSITIONS AND METHOD OF IMPROVING SKIN APPEARANCE THE PROCTER & GAMBLE COMPANY (US) 2000-03-08 EP disclosed
EP-0896522-A1 METHODS OF REGULATING SKIN APPEARANCE WITH VITAMIN B 3? COMPOUND THE PROCTER & GAMBLE COMPANY (US) 1999-02-17 EP disclosed
WO-1998052533-A1 SKIN CARE COMPOSITIONS AND METHOD OF IMPROVING SKIN APPEARANCE THE PROCTER & GAMBLE COMPANY (US) 1998-11-26 WO disclosed
WO-1997039733-A1 METHODS OF REGULATING SKIN APPEARANCE WITH VITAMIN B3 COMPOUND THE PROCTER & GAMBLE COMPANY (US) 1997-10-30 WO disclosed